Sugase M, Minamizawa Y, Kaku S, Fujiwara T, Koizumi Y
Department of Obstetrics and Gynecology, Nagano Red Cross Hospital.
Nihon Sanka Fujinka Gakkai Zasshi. 1988 Jan;40(1):74-80.
During the one year period from February 1986 to January 1987, 839 pregnant women were screened for Chlamydia trachomatis infection of the uterine cervical canal by the enzyme immunoassay (EIA, Chlamydiazyme) method. Out of 768 normal pregnant women positive results were obtained in 21 women for a positive rate of 2.7%. In none of 64 women with spontaneous abortion or 7 women with stillbirth were positive results obtained. In 20 of EIA positive women labor was controlled. Extraordinary maternal abnormalities were not seen through labor and puerperium. Out of 21 babies born to these 20 pregnant women, chlamydial pneumonitis developed in 2 babies (10%) and chlamydial conjunctivitis in 1 baby (5%) and these babies were treated. Urethral samples were taken from 16 husbands of EIA positive women, and they were all EIA negative. As to the correlation between EIA and the culture method using HeLa 229 cells, the consistency rate was 78% (n = 18) for positive results and 100% (n = 66) for negative results. Chlamydial IgG antibodies were assayed in 19 out of 21 cases, and all of them yielded positive results. From these results, the importance of screening for Chlamydia trachomatis infection in our country was affirmed.
在1986年2月至1987年1月的一年期间，采用酶免疫测定法（EIA，衣原体酶免疫测定法）对839名孕妇进行了子宫颈管沙眼衣原体感染筛查。在768名正常孕妇中，21名检测结果呈阳性，阳性率为2.7%。64名自然流产妇女和7名死产妇女中均未获得阳性结果。在20名EIA阳性的孕妇中进行了分娩控制。整个分娩和产褥期未发现特殊的母体异常。在这20名孕妇所生的21名婴儿中，2名婴儿（10%）发生了衣原体肺炎，1名婴儿（5%）发生了衣原体结膜炎，这些婴儿均接受了治疗。从EIA阳性妇女的16名丈夫中采集了尿道样本，结果均为EIA阴性。关于EIA与使用HeLa 229细胞的培养方法之间的相关性，阳性结果的符合率为78%（n = 18），阴性结果的符合率为100%（n = 66）。在21例中的19例中检测了衣原体IgG抗体，结果均为阳性。从这些结果可以肯定在我国进行沙眼衣原体感染筛查的重要性。
