鼠角膜上皮伤口建模。
Murine Corneal Epithelial Wound Modeling.
机构信息
Department of Ophthalmology and Visual Sciences, University of Illinois at Chicago, Chicago, IL, USA.
出版信息
Methods Mol Biol. 2021;2193:175-181. doi: 10.1007/978-1-0716-0845-6_17.
PMID:32808269
Abstract
A murine model of corneal epithelial wounding can be performed using simple injury and imaging methods. Here, we describe the creation of a central corneal epithelial defect using mechanical debridement under ophthalmic microscopic visualization. Subsequent monitoring with vital dye application and slit-lamp bio microscopy (slit-lamp) is described in detail.
摘要
一种使用简单的损伤和成像方法的角膜上皮创伤的小鼠模型可以进行。在这里，我们描述了使用眼科显微镜可视化下的机械清创术来创建中央角膜上皮缺损。随后详细描述了使用活染料应用和裂隙灯生物显微镜（裂隙灯）进行的后续监测。
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