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太田痣背景下的黑色素瘤:皮肤科医生的综述。

Melanoma in the setting of nevus of Ota: a review for dermatologists.

机构信息

Dr. Phillip Frost Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, FL, USA.

出版信息

Int J Dermatol. 2021 May;60(5):523-532. doi: 10.1111/ijd.15135. Epub 2020 Aug 17.

DOI:10.1111/ijd.15135
PMID:32808287
Abstract

Nevus of Ota, also known as oculodermal melanocytosis or nevus fuscoceruleus ophthalmomaxillaris, is a benign dermal melanocytic nevus that most commonly affects Asian women. While the lesion is largely a cosmetic concern, it has the potential to undergo malignant transformation to melanoma. Patients with nevus of Ota often present to a dermatologist at some point for examination or removal with laser therapy. Therefore, it is important for dermatologists to understand the cutaneous and extracutaneous risks these lesions carry and how they may present to further optimize management and appropriate referrals. This review describes the demographic, clinical, and prognostic features of melanoma in the setting of nevus of Ota, divided by the nature of the primary melanoma: cutaneous, orbital, intracranial.

摘要

太田痣,亦称眼皮肤黑素细胞增多症或眼上颌部褐青色痣,是一种常见于亚洲女性的良性真皮黑素细胞痣。尽管病变主要是美容问题,但它有恶变成为黑色素瘤的可能。太田痣患者常在某一时间就诊皮肤科医生进行检查或用激光疗法去除。因此,皮肤科医生了解这些病变的皮肤和皮肤外风险及其表现方式对于进一步优化管理和适当转诊非常重要。本综述按原发性黑色素瘤的性质(皮肤、眼眶、颅内)描述了太田痣背景下黑色素瘤的人口统计学、临床和预后特征。

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Reports (MDPI). 2025 Aug 1;8(3):131. doi: 10.3390/reports8030131.
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Narration of an Uncommon Pediatric Cutaneous Melanoma with Metastasis to Liver: Report of Case with Review on Management Updates.一例罕见的小儿皮肤黑色素瘤伴肝转移的病例报告:病例报告及管理进展综述
Indian J Otolaryngol Head Neck Surg. 2025 Feb;77(2):1125-1128. doi: 10.1007/s12070-024-05289-0. Epub 2024 Dec 31.
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Acquired Bilateral Nevus of Ota-Like Macules: A Case Report.
获得性双侧太田痣样斑:一例报告
Cureus. 2024 Jul 26;16(7):e65453. doi: 10.7759/cureus.65453. eCollection 2024 Jul.
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An update on ophthalmological perspectives in oculodermal melanocytosis (Nevus of Ota).眼皮肤黑素细胞增多症(太田痣)的眼科观点更新。
Graefes Arch Clin Exp Ophthalmol. 2023 Feb;261(2):291-301. doi: 10.1007/s00417-022-05743-1. Epub 2022 Jul 19.
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The spectrum of melanocytic nevi and their clinical implications.黑素细胞痣的光谱及其临床意义。
J Dtsch Dermatol Ges. 2022 Apr;20(4):483-504. doi: 10.1111/ddg.14776.