Dr. Phillip Frost Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, FL, USA.
Int J Dermatol. 2021 May;60(5):523-532. doi: 10.1111/ijd.15135. Epub 2020 Aug 17.
Nevus of Ota, also known as oculodermal melanocytosis or nevus fuscoceruleus ophthalmomaxillaris, is a benign dermal melanocytic nevus that most commonly affects Asian women. While the lesion is largely a cosmetic concern, it has the potential to undergo malignant transformation to melanoma. Patients with nevus of Ota often present to a dermatologist at some point for examination or removal with laser therapy. Therefore, it is important for dermatologists to understand the cutaneous and extracutaneous risks these lesions carry and how they may present to further optimize management and appropriate referrals. This review describes the demographic, clinical, and prognostic features of melanoma in the setting of nevus of Ota, divided by the nature of the primary melanoma: cutaneous, orbital, intracranial.
太田痣,亦称眼皮肤黑素细胞增多症或眼上颌部褐青色痣,是一种常见于亚洲女性的良性真皮黑素细胞痣。尽管病变主要是美容问题,但它有恶变成为黑色素瘤的可能。太田痣患者常在某一时间就诊皮肤科医生进行检查或用激光疗法去除。因此,皮肤科医生了解这些病变的皮肤和皮肤外风险及其表现方式对于进一步优化管理和适当转诊非常重要。本综述按原发性黑色素瘤的性质(皮肤、眼眶、颅内)描述了太田痣背景下黑色素瘤的人口统计学、临床和预后特征。