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单核细胞高密度脂蛋白胆固醇比值作为肠系膜栓塞的一个新的预后因素。

Monocyte High Density Lipoprotein Cholesterol Ratio as a New Prognostic Factor for Mesenteric Embolism.

机构信息

Department of General Surgery, Health Science University, Adana City Research and Training Hospital, Turkey.

出版信息

J Coll Physicians Surg Pak. 2020 Jul;30(7):688-693. doi: 10.29271/jcpsp.2020.07.688.

Abstract

OBJECTIVE

To determine the effectiveness of the ratio of monocyte count to high density lipoprotein cholesterol in predicting in-hospital mortality.

STUDY DESIGN

Descriptive study.

PLACE AND DURATION OF STUDY

Intensive Care Unite, Adana Numune Research and Training Hospital, Turkey, from January 2018 to December 2019.

METHODOLOGY

Patients admitted to the intensive care unit with the diagnosis of mesenteric embolism were included in the study. Monocyte count and high-density lipoprotein cholesterol (HDL) values were determined. Monocyte HDL Ratio (MHR) values of the patients were calculated. SPSS 26 package programme was used to investigate the effectiveness of MHR in predicting mortality.

RESULTS

The mean age of the 81 patients was 69.9 ±10.6 years. In the group with mortality, the number of monocytes and MHR were significantly higher than the group without mortality (p<0.05). In the mortality group, HDL value was significantly lower (p<0.05) than the non-mortality group. Sensitivity of the MHR cutoff value of 19 was 81.8%, positive predictive value was 96.4%, specificity value was 97.9%, negative predictive value was 88.7%.

CONCLUSION

For patients diagnosed with acute mesenteric embolism, the use of predictors in terms of mortality estimation is very important for the faster implementation of treatment modalities. MHR value can be used as a strong predictor. Key Words: Mesenteric embolism, Monocyte, HDL cholesterol, MHR, Mortality.

摘要

目的

确定单核细胞计数与高密度脂蛋白胆固醇比值预测住院死亡率的有效性。

研究设计

描述性研究。

地点和研究时间

土耳其阿达纳努梅恩研究和培训医院重症监护病房,2018 年 1 月至 2019 年 12 月。

方法

将诊断为肠系膜栓塞并收入重症监护病房的患者纳入本研究。测定单核细胞计数和高密度脂蛋白胆固醇(HDL)值。计算患者的单核细胞 HDL 比值(MHR)值。使用 SPSS 26 包程序来研究 MHR 在预测死亡率方面的有效性。

结果

81 例患者的平均年龄为 69.9 ±10.6 岁。在死亡组中,单核细胞和 MHR 数量明显高于无死亡组(p<0.05)。在死亡组中,HDL 值明显低于非死亡组(p<0.05)。MHR 截断值为 19 时的灵敏度为 81.8%,阳性预测值为 96.4%,特异性值为 97.9%,阴性预测值为 88.7%。

结论

对于诊断为急性肠系膜栓塞的患者,使用死亡率预测指标对于更快地实施治疗方法非常重要。MHR 值可作为强有力的预测指标。关键词:肠系膜栓塞;单核细胞;HDL 胆固醇;MHR;死亡率。

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