Department of Obstetrics and Gynecology, Eskisehir Osmangazi University, Faculty of Medicine, Eskisehir, Turkey.
Department Obstetric And Women's Disease Nursing, Eskisehir Osmangazi University, Faculty of Health Sciences, Eskisehir, Turkey.
J Psychosom Obstet Gynaecol. 2022 Jun;43(2):114-121. doi: 10.1080/0167482X.2020.1806819. Epub 2020 Aug 19.
This study evaluated the level of fear and anxiety related to the COVID-19 outbreak, in infertile women whose ART cycles were delayed due to the pandemic.
An online survey was sent to women whose ART cycles were postponed due to the COVID-19 outbreak between April and May 2020. The study population were 101 participants. The main outcome measure is to determine the levels of fear and anxiety in infertile women by using the Spielberger State-Trait Anxiety Inventory (STAI-T and STAI-S) and Fear of COVID-19 scale (FCV-19S). The relationship of the COVID-19 outbreak with the willingness to go ahead with the desire for pregnancy was also assessed.
The state-anxiety levels were significantly higher in women above 35 years (45.0 ± 5.2 vs. 42.2 ± 4.5, = 0.006). Women with diminished ovarian reserve had a higher state-anxiety compared to other causes, but were not found to be significant (44.7 ± 5.2 vs. 42.5 ± 5.0, = 0.173). Women who thought that the possibility of not being able to get pregnant was more important than being infected with the COVID-19 had higher anxiety levels than women who thought just the opposite. The diminished ovarian reserve and high duration of infertility were found to be significantly associated with higher anxiety levels (OR = 2.5, < 0.05). The diminished ovarian reserve and previous ART failure significantly predicted the presence of clinical state-anxiety.
The state-anxiety was found to be higher in women whose cycles were postponed due to the outbreak and the presence of diminished ovarian reserve also significantly affected anxiety levels. Further research is needed to assess whether COVID-19 will have any impact on ART treatments in the next few years.
本研究评估了因 COVID-19 大流行而推迟辅助生殖技术（ART）周期的不孕女性对相关疾病的恐惧和焦虑水平。
2020 年 4 月至 5 月期间，我们向因 COVID-19 大流行而推迟 ART 周期的女性发送了在线调查。研究人群为 101 名参与者。主要观察指标是使用 Spielberger 状态-特质焦虑量表（STAI-T 和 STAI-S）和 COVID-19 恐惧量表（FCV-19S）来确定不孕女性的恐惧和焦虑水平。还评估了 COVID-19 大流行与继续妊娠愿望的关系。
35 岁以上女性的状态焦虑水平明显更高（45.0±5.2 与 42.2±4.5，=0.006）。卵巢储备功能减退的女性与其他原因相比，状态焦虑更高，但无统计学意义（44.7±5.2 与 42.5±5.0，=0.173）。认为无法怀孕的可能性比感染 COVID-19 更重要的女性比认为恰恰相反的女性焦虑水平更高。卵巢储备功能减退和较长的不孕时间与较高的焦虑水平显著相关（OR=2.5，<0.05）。卵巢储备功能减退和既往 ART 失败显著预测了临床状态焦虑的存在。
由于疫情而推迟周期的女性焦虑水平更高，卵巢储备功能减退也显著影响焦虑水平。需要进一步研究评估 COVID-19 在未来几年内是否会对 ART 治疗产生任何影响。
