Cao Lian-Bao, Hao Qianjie, Liu Yan, Sun Qiang, Wu Bing, Chen Lili, Yan Lei
School of Medicine, Cheeloo College of Medicine, Shandong University, Jinan, China.
Department of Obstetrics and Gynecology, The Eighth People's Hospital of Xinjiang Uygur Autonomous Region, Urumqi, China.
Front Psychiatry. 2021 Jul 22;12:647483. doi: 10.3389/fpsyt.2021.647483. eCollection 2021.
Infertility usually causes mental health problems for patients and unfavorable emotions such as anxiety and depression can have an adverse effect on women's normal pregnancy. We aimed to compare the anxiety level between infertile female patients in quarantined and non-quarantined areas during the second wave of COVID-19 epidemic. A total of 759 infertile women were included in this cross-sectional study conducted through an online survey. Anxiety was measured by the State-Trait Anxiety Inventory (STAI) tool. Participants were divided into the quarantined group (QG) and non-quarantined group (Non-QG). Independent sample -test and chi-square test were performed to examine the difference between the two groups. There was no significant difference in the average STAI score of the two groups of infertile women, but responses to the emotional state showed that women in the QG had a higher tendency to be anxious. Participants in QG spent more time paying attention to the dynamics of the epidemic every day, and their sleep ( < 0.01) and mood conditions were worse ( < 0.01) than in the Non-QG. The family relationship of QG is more tense than non-QG. Through the research on the infertility treatment information of the overall research population, it is found the average STAI-State (STAI-S) ( = 0.031) score and STAI-Trait (STAI-T) ( = 0.005) score of women who were infertile for more than 3 years were significantly higher than those of women with <2 years. The STAI-T score of infertile women who underwent fertilization (IVF) was higher than that of non-IVF women ( = 0.007), but no significant difference was observed with the STAI-S score. To conclude, although the second wave of quarantine during COVID-19 epidemic did not significantly increase anxiety in infertile women, it did lead to an increase in other negative emotions and worse family relationships. Patients with long-term infertility treatment and those who have had IVF are more anxious subgroups.
不孕症通常会给患者带来心理健康问题，焦虑和抑郁等不良情绪会对女性正常受孕产生不利影响。我们旨在比较第二波新冠疫情期间隔离区和非隔离区不孕女性患者的焦虑水平。本横断面研究通过在线调查共纳入759名不孕女性。采用状态-特质焦虑量表（STAI）工具测量焦虑程度。参与者被分为隔离组（QG）和非隔离组（Non-QG）。进行独立样本t检验和卡方检验以检验两组之间的差异。两组不孕女性的平均STAI得分无显著差异，但对情绪状态的反应表明，QG组女性焦虑倾向更高。QG组参与者每天花更多时间关注疫情动态，其睡眠（P<0.01）和情绪状况比Non-QG组更差（P<0.01）。QG组的家庭关系比非隔离组更紧张。通过对总体研究人群的不孕症治疗信息研究发现，不孕超过3年的女性的平均状态焦虑量表（STAI-S）得分（P = 0.031）和特质焦虑量表（STAI-T）得分（P = 0.005）显著高于不孕<2年的女性。接受体外受精（IVF）的不孕女性的STAI-T得分高于未接受IVF的女性（P = 0.007），但STAI-S得分未观察到显著差异。总之，虽然新冠疫情期间的第二波隔离并未显著增加不孕女性的焦虑，但确实导致了其他负面情绪增加和家庭关系恶化。长期接受不孕症治疗的患者和接受过IVF的患者是焦虑程度更高的亚组。
