Suppr超能文献

综述:磁弹性凝胶基质中磁控治疗的远程调控。

Review: Remotely controlled magneto-regulation of therapeutics from magnetoelastic gel matrices.

机构信息

The Institute of Nanotechnology and Advanced Materials, Department of Chemistry, Bar-Ilan University, Ramat-Gan 52900, Israel.

The Institute of Nanotechnology and Advanced Materials, Department of Chemistry, Bar-Ilan University, Ramat-Gan 52900, Israel.

出版信息

Biotechnol Adv. 2020 Nov 15;44:107611. doi: 10.1016/j.biotechadv.2020.107611. Epub 2020 Aug 18.

Abstract

Surface active magnetic nanoparticles especially superparamagnetic iron oxides are already occupying a major domain in medical therapeutics. Arresting of these magnetic nanoparticles into polymer hydrogel is a spatial assembly of nanoparticles that serves the precise delivery of drug molecules. Magnetic hydrogels are very less cultured area still in the biomedical field. This review embraces how the external magnetic field (either static or oscillating) affects the payload release from the hydrogel matrix and their magneto-regulative deformation. Besides these, we also discussed how the ferrosponge and biphasic ferrogel based scaffold type systems impact over the release kinetics and tunability of drug release behaviours.

摘要

表面活性磁性纳米粒子,特别是超顺磁性氧化铁,已经在医学治疗领域占据了主要地位。将这些磁性纳米粒子固定在聚合物水凝胶中是纳米粒子的空间组装,用于精确递送药物分子。磁性水凝胶在生物医学领域仍然是一个研究较少的领域。本综述探讨了外磁场(无论是静态还是振荡)如何影响水凝胶基质中有效负载的释放及其磁调节变形。除此之外,我们还讨论了基于铁海绵和双相铁凝胶的支架型系统如何影响药物释放动力学和释放行为的可调性。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验