Pneumonia in an SLE Patient: A Case Study.

The risk of opportunistic fungal infections is high in immunocompromised patients. The genus is common and diverse in nature. However, it rarely causes infection in humans. Here, we reported a case of pneumonia in a systemic lupus erythematosus (SLE) patient, and the morphological characteristics of were also described. The patient was a 64-year-old female. She had been diagnosed with SLE and membranous lupus nephritis 10 months previously. Her medications included methylprednisolone, cyclosporine, and hydroxychloroquine. She was admitted because of fever and diagnosed with pneumonia. was isolated from sputum and bronchoalveolar lavage (BAL) samples. BAL fluid stained with multiple stains showed the presence of somewhat dichotomously branching septate fungal hyphae. was identified, and its morphological features were described. Antibiotic susceptibility profiles showed that this strain had higher minimum inhibitory concentration (MIC) values in response to multiple antifungal drugs. The patient died 10 days after diagnosis. To the best of our knowledge, this report is the second to demonstrate that causes infection and is the first to present an infection (pneumonia) caused by i in an SLE patient. Clinical and laboratory personnel should be aware that the genus also contains pathogenic bacteria that cannot simply be treated as contaminants, especially in immunosuppressed patients.