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在儿童时期,难以维持长时间的注意力集中和注意力缺陷/多动症状存在共同的遗传影响。

Difficulties maintaining prolonged fixation and attention-deficit/hyperactivity symptoms share genetic influences in childhood.

机构信息

Department of Psychology, Uppsala University, Uppsala, Sweden; Center of Neurodevelopmental Disorders at Karolinska Institutet (KIND), Dept of Women's and Children's Health, Karolinska Institutet, Stockholm, Sweden; Swedish Collegium for Advanced Study (SCAS), Uppsala, Sweden.

Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.

出版信息

Psychiatry Res. 2020 Nov;293:113384. doi: 10.1016/j.psychres.2020.113384. Epub 2020 Aug 18.

Abstract

This study investigated the association between the ability to maintain prolonged (2-minute) fixation on a visual target and ADHD traits in a sample consisting of 120 monozygotic and 120 dizygotic twin pairs, aged 9 to 14 years. More intrusive saccades during the task was associated with higher level of parent-reported ADHD traits. Both intrusive saccades and ADHD symptoms had high heritability estimates, and there was a moderate genetic correlation between number of intrusive saccades and ADHD. This study suggests that inability to maintain ocular fixation for longer times is etiologically linked to ADHD traits in the general population.

摘要

本研究调查了在一个由 120 对同卵双胞胎和 120 对异卵双胞胎组成的样本中,持续(2 分钟)注视视觉目标的能力与 ADHD 特征之间的关系,这些双胞胎的年龄在 9 到 14 岁之间。在任务过程中,更多的侵入性眼跳与更高水平的父母报告 ADHD 特征相关。侵入性眼跳和 ADHD 症状都有很高的遗传估计值,并且侵入性眼跳的数量与 ADHD 之间存在中度的遗传相关性。这项研究表明,在普通人群中,无法长时间保持眼球固定与 ADHD 特征在病因上有关。

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