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患有皮肤、眼睛和口腔感染的早产新生儿出现双侧急性视网膜坏死，并伴有玻璃体和视网膜下出血。

Bilateral acute retinal necrosis in premature newborn with skin, eye, and mouth infection presenting with vitreous and subretinal hemorrhage.

作者信息

Khurram Darakshanda, Ali Syed M, Kozak Igor

机构信息

Moorfield Eye Hospitals UAE, Dubai, U.A.E.

出版信息

Indian J Ophthalmol. 2020 Sep;68(9):2009-2011. doi: 10.4103/ijo.IJO_1038_20.

DOI:10.4103/ijo.IJO_1038_20
PMID:32823461
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7690509/
Abstract

A premature newborn with systemic sepsis due to Candida albicans and parapsilosis developed skin, eye, and mouth herpetic infection. Ocular disease presented atypically with vitritis and pre and subretinal hemorrhage due to herpes simplex virus-1 confirmed fulminant bilateral acute retinal necrosis. Pars plana vitrectomy revealed necrotizing retinitis with poor visual prognosis. The baby has survived suffering from multiple morbidities which include post-hemorrhagic hydrocephalus, chronic lung disease, patent ductus arteriosus, and developmental delay.

摘要

一名因白色念珠菌和近平滑念珠菌感染导致全身败血症的早产新生儿发生了皮肤、眼睛和口腔疱疹感染。眼部疾病表现不典型，因单纯疱疹病毒-1确诊为暴发性双侧急性视网膜坏死，出现了玻璃体炎以及视网膜前和视网膜下出血。玻璃体切割术显示为坏死性视网膜炎，视力预后不佳。该婴儿存活下来，但患有多种疾病，包括出血后脑积水、慢性肺病、动脉导管未闭和发育迟缓。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7e15/7690509/e68615926b9f/IJO-68-2009-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7e15/7690509/dc88ed046245/IJO-68-2009-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7e15/7690509/d17c85d903d9/IJO-68-2009-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7e15/7690509/e68615926b9f/IJO-68-2009-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7e15/7690509/dc88ed046245/IJO-68-2009-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7e15/7690509/d17c85d903d9/IJO-68-2009-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7e15/7690509/e68615926b9f/IJO-68-2009-g003.jpg

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本文引用的文献

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Fulminant bilateral acute retinal necrosis complicated with secondary herpes simplex type-1 viral encephalitis: A case report.暴发性双侧急性视网膜坏死并发1型单纯疱疹病毒性脑炎：一例报告
Medicine (Baltimore). 2019 Aug;98(35):e17001. doi: 10.1097/MD.0000000000017001.
2
BILATERAL ACUTE RETINAL NECROSIS: A Case Series.双侧急性视网膜坏死：病例系列。
Retina. 2020 Jan;40(1):145-153. doi: 10.1097/IAE.0000000000002341.
3
Bilateral Acute Retinal Necrosis: Clinical Features and Outcomes in a Multicenter Study.双侧急性视网膜坏死：一项多中心研究的临床特征和结局。
Ocul Immunol Inflamm. 2019;27(7):1090-1098. doi: 10.1080/09273948.2018.1501494. Epub 2018 Jul 30.
4
Real-time polymerase chain reaction in acute retinal necrosis following encephalitis.脑炎后继发急性视网膜坏死的实时聚合酶链反应。
Indian J Ophthalmol. 2018 Feb;66(2):322-324. doi: 10.4103/ijo.IJO_748_17.
5
Acute retinal necrosis in a neonate.新生儿急性视网膜坏死
Retin Cases Brief Rep. 2013 Fall;7(4):406-8. doi: 10.1097/ICB.0b013e318297f6d5.
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Bilateral Acute Retinal Necrosis with Concurrent Retinopathy of Prematurity in Two Neonates.两名新生儿双侧急性视网膜坏死并发早产儿视网膜病变
Ocul Immunol Inflamm. 2016;24(1):115-7. doi: 10.3109/09273948.2014.916724. Epub 2014 May 15.
7
Neonatal herpes simplex virus type-1 central nervous system disease with acute retinal necrosis.
Pediatr Infect Dis J. 2014 Apr;33(4):424-6. doi: 10.1097/INF.0000000000000137.
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