0.01%阿托品滴眼液对近视儿童脉络膜厚度的影响。
Effect of 0.01% atropine eye drops on choroidal thickness in myopic children.
作者信息
Li W, Jiang R, Zhu Y, Zhou J, Cui C
机构信息
Department of Ophthalmology, Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China; Shanghai Key Laboratory of Orbital Diseases and Ocular Oncology, Shanghai, China.
Department of Ophthalmology, Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China; Shanghai Key Laboratory of Orbital Diseases and Ocular Oncology, Shanghai, China.
出版信息
J Fr Ophtalmol. 2020 Nov;43(9):862-868. doi: 10.1016/j.jfo.2020.04.023. Epub 2020 Aug 20.
PURPOSE
To examine the effects of low-dose atropine on the choroidal thickness (CT) of young children in Shanghai, China, as well as the ocular biometrics of myopic patients.
METHODS
A total of 59 eyes of 35 myopic children had subfoveal CT and ocular biometry measurements taken before and after 2weeks, 4weeks, and 8weeks of treatment with 0.01% atropine. All eyes were measured using swept-source optical coherence tomography. CT and changes in it were also recorded.
RESULTS
The choroid exhibited significant and continuous thickening under the fovea after patients were treated with 0.01% atropine. The magnitude of change in CT varied with the location and with the duration of treatment. The greatest change was observed in the fovea. There was no significant relationship between changes in subfoveal CT and axial length.
CONCLUSIONS
Using 0.01% atropine eye drops significantly increased CT in eyes of young myopic children, by variable magnitude depending upon location.
目的
研究低剂量阿托品对中国上海幼儿脉络膜厚度（CT）以及近视患者眼部生物特征的影响。
方法
35名近视儿童的59只眼睛在使用0.01%阿托品治疗2周、4周和8周之前及之后进行了黄斑中心凹下CT测量和眼部生物测量。所有眼睛均使用扫频光学相干断层扫描进行测量。同时记录CT及其变化情况。
结果
使用0.01%阿托品治疗后，脉络膜在黄斑中心凹下呈现出显著且持续的增厚。CT的变化幅度因位置和治疗持续时间而异。在黄斑中心凹观察到的变化最大。黄斑中心凹下CT的变化与眼轴长度之间无显著关系。
结论
使用0.01%阿托品滴眼液可显著增加年轻近视儿童眼睛的CT，其增加幅度因位置而异。
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