Department of Gastroenterology, Nagano Red Cross Hospital, Nagano, Japan.
Department of Medicine, Division of Gastroenterology and Hepatology, Shinshu University School of Medicine, 3-1-1 Asahi, Matsumoto, 390-8621, Japan.
BMC Gastroenterol. 2020 Aug 24;20(1):286. doi: 10.1186/s12876-020-01430-9.
Pancreatic panniculitis is a rare skin manifestation in pancreatic disease patients that most frequently develops on the lower legs. We report the unique case of a 68-year-old man who suffered from pancreatic panniculitis on his trunk associated with acute pancreatitis due to an intraductal papillary mucinous neoplasm.
A 68-year-old man complained of a 2-day history of a tender subcutaneous nodule on his trunk. Laboratory tests and abdominal contrast computed tomography were consistent with acute pancreatitis due to an intraductal papillary mucinous neoplasm. A skin biopsy of the nodule histologically displayed lobular panniculitis with characteristic "ghost cells", which indicated pancreatic panniculitis.
In order to avoid a missed or delayed diagnosis, clinicians should bear in mind that pancreatic panniculitis can be the first manifestation of pancreatic disease when encountering subcutaneous nodules on the trunk.
胰腺性脂膜炎是胰腺疾病患者一种罕见的皮肤表现，多发生于小腿。我们报告了一例独特的病例，一名 68 岁男性因胰管内乳头状黏液性肿瘤并发急性胰腺炎而出现了累及躯干的胰腺性脂膜炎。
一名 68 岁男性因躯干部位出现压痛性皮下结节而就诊，病程 2 天。实验室检查和腹部对比增强 CT 结果符合胰管内乳头状黏液性肿瘤并发的急性胰腺炎。结节的皮肤活检组织学显示小叶性脂膜炎，伴有特征性的“鬼影细胞”，提示胰腺性脂膜炎。
为避免漏诊或延误诊断，临床医生在遇到躯干部位的皮下结节时，应牢记胰腺性脂膜炎可能是胰腺疾病的首发表现。
