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起源于颈段食管入口黏膜斑的腺癌：小病变的恶性潜能

Adenocarcinoma Arising From a Cervical Esophageal Inlet Patch: The Malignant Potential of a Small Lesion.

作者信息

Dziadkowiec Karolina N, Sánchez-Luna Sergio A, Stawinski Peter, Proenza Jose

机构信息

Internal Medicine, University of Miami, John F. Kennedy Regional Campus, Atlantis, USA.

Center for Advanced Therapeutic Endoscopy/Division of Gastroenterology, Hepatology and Nutrition, Allegheny Health Network/Allegheny Center for Digestive Health, Pittsburgh, USA.

出版信息

Cureus. 2020 Jul 19;12(7):e9284. doi: 10.7759/cureus.9284.

DOI:10.7759/cureus.9284
PMID:32832282
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7437138/
Abstract

Inlet patches (IP) are heterotopic lesions consisting of gastric mucosa. Commonly located in the cervical esophagus, it is believed that they are remnants of fetal columnar epithelium arising from incomplete replacement during embryogenesis. A rare complication of IP is the development of proximal esophageal adenocarcinoma. We report a case of a 59-year-old male with intractable cough and dysphagia that was found to have a malignant transformation of an IP.

摘要

入口斑（IP）是由胃黏膜构成的异位病变。通常位于颈段食管，据信它们是胚胎发育过程中由于不完全替代而产生的胎儿柱状上皮的残余物。IP的一种罕见并发症是近端食管腺癌的发生。我们报告一例59岁男性，有顽固性咳嗽和吞咽困难，经检查发现其入口斑发生了恶性转化。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0a5a/7437138/ad18d7c64b1b/cureus-0012-00000009284-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0a5a/7437138/0eb214af9db3/cureus-0012-00000009284-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0a5a/7437138/5768c5828ccc/cureus-0012-00000009284-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0a5a/7437138/b17547e325e4/cureus-0012-00000009284-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0a5a/7437138/ad18d7c64b1b/cureus-0012-00000009284-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0a5a/7437138/0eb214af9db3/cureus-0012-00000009284-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0a5a/7437138/5768c5828ccc/cureus-0012-00000009284-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0a5a/7437138/b17547e325e4/cureus-0012-00000009284-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0a5a/7437138/ad18d7c64b1b/cureus-0012-00000009284-i04.jpg

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本文引用的文献

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Correction: Adenocarcinoma Arising From a Cervical Esophageal Inlet Patch: The Malignant Potential of a Small Lesion.更正：起源于宫颈食管入口斑的腺癌：小病变的恶性潜能
Cureus. 2022 Sep 13;14(9):c74. doi: 10.7759/cureus.c74. eCollection 2022 Sep.
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Cervical inlet patch: new insights into diagnosis and endoscopic therapy.宫颈入口斑块：诊断与内镜治疗的新见解
Frontline Gastroenterol. 2018 Jul;9(3):214-220. doi: 10.1136/flgastro-2017-100855. Epub 2017 Nov 9.
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Heterotopic gastric mucosa of the proximal oesophagus (inlet patch): endoscopic prevalence, histological and clinical characteristics in paediatric patients.
小儿近端食管异位胃黏膜（入口斑）：内镜下患病率、组织学及临床特征
Eur J Gastroenterol Hepatol. 2014 Oct;26(10):1139-45. doi: 10.1097/MEG.0000000000000177.
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Is cervical inlet patch important clinical problem?宫颈内口修补术是重要的临床问题吗？
Int J Biomed Sci. 2014 Jun;10(2):129-35.
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Symptomatic gastric inlet patches in children treated with argon plasma coagulation: a case series.氩等离子体凝固治疗儿童有症状的胃入口黏膜斑：病例系列
J Interv Gastroenterol. 2012 Apr;2(2):91-93. doi: 10.4161/jig.22207. Epub 2012 Apr 1.
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World J Gastroenterol. 2013 Jan 21;19(3):331-8. doi: 10.3748/wjg.v19.i3.331.
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A clinicopathologic study of esophageal 860 benign and malignant lesions in 910 cases of consecutive esophageal biopsies.对910例连续食管活检病例中的860例食管良恶性病变进行的临床病理研究。
Int J Clin Exp Pathol. 2013;6(2):191-8. Epub 2013 Jan 15.
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Esophageal inlet patch.食管入口斑
Radiol Res Pract. 2011;2011:460890. doi: 10.1155/2011/460890. Epub 2011 Mar 30.
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Erupted cysts in the cervical esophagus result in gastric inlet patches.宫颈段食管的破裂囊肿会导致胃入口黏膜异位。
Gastrointest Endosc. 2010 Sep;72(3):603-5. doi: 10.1016/j.gie.2010.05.008.
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Inlet patch of gastric mucosa in upper esophagus causing chronic cough and vocal cord dysfunction.位于食管上段的胃黏膜内疝导致慢性咳嗽和声带功能障碍。
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