Abdul-Baki Kian, Pavurala Ravi, Salim Hamza, Menon Raakhi, Bigham Lindsay, Thaker Harshwardhan, Reep Gabriel, Parupudi Sreeram
Internal Medicine, University of Texas Medical Branch, Galveston, TX.
Department of Gastroenterology and Hepatology, University of Texas Medical Branch, Galveston, TX.
ACG Case Rep J. 2023 Jul 26;10(7):e01096. doi: 10.14309/crj.0000000000001096. eCollection 2023 Jul.
Proximal esophageal adenocarcinoma is extremely rare. A gastric inlet patch is a lesion of ectopic gastric mucosa usually found in the cervical esophagus and is considered an incidental finding, but there is a risk for malignant transformation. We report the case of a 50-year-old male with gastroesophageal reflux disease with a 6-month history of progressive dysphagia and 20-pound weight loss. Upper endoscopy showed a malignant stricture with adjacent gastric inlet patch. Biopsies obtained from endoscopic ultrasonography showed adenocarcinoma. This case re-emphasizes careful examination of ectopic gastric mucosa and to consider biopsy if there is suspicion for malignant transformation.
近端食管腺癌极为罕见。胃入口斑是一种通常在颈段食管发现的异位胃黏膜病变，被视为偶然发现，但存在恶变风险。我们报告一例50岁男性，患有胃食管反流病，有6个月进行性吞咽困难病史且体重减轻20磅。上消化道内镜检查显示有恶性狭窄及相邻的胃入口斑。经内镜超声检查获取的活检显示为腺癌。该病例再次强调要仔细检查异位胃黏膜，若怀疑有恶变则考虑进行活检。
