Jeelani Hafiz Muhammad, Sheikh Muhammad Mubbashir, Sheikh Belaal, Mahboob Hafiz, Bharat Anchit
Internal Medicine, Rosalind Franklin University of Medicine and Science, McHenry, USA.
Oncology, Northwestern University Feinberg School of Medicine, Chicago, USA.
Cureus. 2020 Jul 20;12(7):e9294. doi: 10.7759/cureus.9294.
Exogenous lipoid pneumonia is a rare and frequently misdiagnosed lung disease. It occurs as an inflammatory reaction secondary to either aspiration or inhalation of lipids. Our patient had a history significant for recurrent pneumonia and the use of mineral oil for chronic constipation. A chest computed tomography showed multifocal consolidative opacities with areas of low attenuation, highly suspicious of exogenous lipid pneumonia. The diagnosis was confirmed with combined bronchoalveolar lavage and transbronchial lung biopsy that showed lipid-laden macrophages consistent with exogenous lipoid pneumonia. After thorough medication review, apart from mineral oil, no other contributing factors were found. A diagnosis of exogenous lipoid pneumonia associated with the use of mineral oil made and successfully managed by stopping the offending agent and supportive antibiotics.
外源性类脂性肺炎是一种罕见且常被误诊的肺部疾病。它是由于脂质吸入或误吸继发的炎症反应。我们的患者有复发性肺炎病史,并且长期使用矿物油治疗慢性便秘。胸部计算机断层扫描显示多灶性实变影伴低密度区,高度怀疑为外源性类脂性肺炎。经支气管肺泡灌洗和经支气管肺活检联合检查确诊,结果显示含脂巨噬细胞,符合外源性类脂性肺炎。在全面的药物审查后,除矿物油外,未发现其他相关因素。诊断为与使用矿物油相关的外源性类脂性肺炎,通过停用致病药物和使用支持性抗生素成功治疗。