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腹腔中迁移抑制活性的存在与产生。

Presence and production of migration inhibitory activity in the peritoneal cavity.

作者信息

Van Maarsseveen A C

出版信息

Immunology. 1977 Jun;32(6):893-8.

PMID:328384
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1445459/
Abstract

The presence of migration inhibitory (MI) activity was investigated in the delayed hypersensitivity (DH) reaction induced by i.p. injection of PPD into FCA-sensitized guinea-pigs. Peritoneal exudates were studied at several times before and after the induction of the DH reaction and a non-immune control inflammation. Lymphokine (LK) fractions were prepared from individual exudates and tested in a conventional macrophage migration inhibition assay at concentrations determined to occur in vivo. The results suggest a continuous local production of MI activity and an augmented production during development of a DH reaction.

摘要

通过腹腔注射结核菌素纯蛋白衍生物（PPD）至弗氏完全佐剂（FCA）致敏的豚鼠体内诱导迟发型超敏反应（DH），研究其中迁移抑制（MI）活性的存在情况。在诱导DH反应和非免疫对照炎症之前及之后的多个时间点对腹腔渗出液进行研究。从各个渗出液中制备淋巴细胞因子（LK）组分，并在传统的巨噬细胞迁移抑制试验中，以体内测定的浓度进行检测。结果表明MI活性存在持续的局部产生，且在DH反应发展过程中产生增加。

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Presence and production of migration inhibitory activity in the peritoneal cavity.腹腔中迁移抑制活性的存在与产生。
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本文引用的文献

1
'Lymphokines': molecular mediators of cellular immune responses in animals and man.“淋巴因子”：动物和人类细胞免疫反应的分子介质。
Proc R Soc Med. 1970 Sep;63(9):899-902. doi: 10.1177/003591577006300917.
2
The peritoneal exudate lymphocyte. I. Differences in antigen responsiveness between peritoneal exudate and lymph node lymphocytes from immunized guinea pigs.腹膜渗出淋巴细胞。I. 免疫豚鼠腹膜渗出淋巴细胞与淋巴结淋巴细胞抗原反应性的差异。
J Exp Med. 1971 Nov 1;134(5):1170-86. doi: 10.1084/jem.134.5.1170.
3
The mechanism of action of soluble lymphocytic mediators. I. A pulse exposure test for the measurement of macrophage migration inhibitory factor.可溶性淋巴细胞介质的作用机制。I. 用于测量巨噬细胞移动抑制因子的脉冲暴露试验。
Immunology. 1973 Jun;24(6):1027-34.
4
Lymphokine activity in vivo in relation to circulating monocyte levels and delayed skin reactivity.体内淋巴因子活性与循环单核细胞水平及皮肤迟发型反应的关系。
J Immunol. 1974 Apr;112(4):1540-7.
5
Mechanism of action of migration inhibitory factor (MIF). I. Evidence for a receptor for MIF present on the peritoneal macrophage but not on the alveolar macrophage.迁移抑制因子（MIF）的作用机制。I. 腹膜巨噬细胞存在MIF受体而肺泡巨噬细胞不存在该受体的证据。
J Exp Med. 1972 Sep 1;136(3):589-603. doi: 10.1084/jem.136.3.589.
6
Activity of migration inhibitory factor in the absence of antigen.
J Immunol. 1972 Aug;109(2):201-6.
7
Role of lymphocyte activation products (LAP) in cell-mediated immunity. I. Preparation and partial purification of guinea-pig LAP.淋巴细胞激活产物（LAP）在细胞介导免疫中的作用。I. 豚鼠LAP的制备及部分纯化
Clin Exp Immunol. 1972 Jan;10(1):25-47.
8
Studies on migration inhibitory factor (MIF): recovery of MIF activity after purification by gel filtration and disc electrophoresis.迁移抑制因子（MIF）的研究：通过凝胶过滤和圆盘电泳纯化后MIF活性的恢复。
Cell Immunol. 1970 May;1(1):133-45. doi: 10.1016/0008-8749(70)90066-3.
9
Studies on delayed hypersensitivity pleural exudates in guinea pigs. I. Demonstration of substances in the cell-free exudate which cause inhibition of mononuclear cell migration in vitro.豚鼠迟发型超敏反应性胸腔渗出液的研究。I. 无细胞渗出液中引起体外单核细胞迁移抑制的物质的证实。
Immunology. 1976 Apr;30(4):505-11.

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