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1
Presence and production of migration inhibitory activity in the peritoneal cavity.腹腔中迁移抑制活性的存在与产生。
Immunology. 1977 Jun;32(6):893-8.
2
Accumulation of T cells and local anti-PPD antibody production in lymphokine-mediated chronic peritoneal inflammation in the guinea pig.豚鼠中细胞因子介导的慢性腹膜炎中T细胞的积聚及局部抗结核菌素纯蛋白衍生物抗体的产生。
J Pathol. 1980 Sep;132(1):23-33. doi: 10.1002/path.1711320104.
3
Studies on delayed hypersensitivity pleural exudates in guinea pigs. I. Demonstration of substances in the cell-free exudate which cause inhibition of mononuclear cell migration in vitro.豚鼠迟发型超敏反应性胸腔渗出液的研究。I. 无细胞渗出液中引起体外单核细胞迁移抑制的物质的证实。
Immunology. 1976 Apr;30(4):505-11.
4
Lymphokines in sensitized rats. I. Migration inhibitory factor(s) from specifically stimulated thymocytes in vitro.致敏大鼠中的淋巴细胞因子。I. 体外特异性刺激胸腺细胞产生的迁移抑制因子
Int Arch Allergy Appl Immunol. 1975;49(4):491-503.
5
The activation of mononuclear phagocytes in vitro: immunologically mediated enhancement.体外单核吞噬细胞的激活：免疫介导的增强作用。
J Reticuloendothel Soc. 1973 Dec;14(6):550-70.
6
Studies on mechanisms of immobilization of mononuclear cells in the delayed hypersensitivity (DH) reaction.迟发型超敏反应（DH）中单核细胞固定机制的研究。
Agents Actions. 1976 Feb;6(1-3):16-27. doi: 10.1007/BF01972181.
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Desensitization: effects on cutaneous and peritoneal manifestations of delayed hypersensitivity in relation to lymphokine production.脱敏作用：与淋巴因子产生相关的对迟发型超敏反应的皮肤和腹膜表现的影响
J Immunol. 1975 Dec;115(6):1657-61.
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Studies on delayed hypersensitivity pleural exudates in guinea-pigs. II. The interrelationship of monocytic and lymphocytic cells with respect to migration activity.豚鼠迟发型超敏反应性胸腔渗出液的研究。II. 单核细胞与淋巴细胞在迁移活性方面的相互关系。
Immunology. 1976 Apr;30(4):513-9.
9
Antigen-enhanced glucosamine incorporation by peritoneal macrophages in cell-mediated hypersensitivity. I. Studies on biology and mechanism.细胞介导的超敏反应中腹膜巨噬细胞抗原增强的氨基葡萄糖掺入。I.生物学和机制研究。
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The adjuvant activity of mycobacterial RNA preparations and synthetic polynucleotides for induction of delayed hypersensitivity to purified protein derivative in guinea pigs.分枝杆菌RNA制剂和合成多核苷酸对豚鼠诱导对纯化蛋白衍生物迟发型超敏反应的佐剂活性。
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本文引用的文献

1
'Lymphokines': molecular mediators of cellular immune responses in animals and man.“淋巴因子”：动物和人类细胞免疫反应的分子介质。
Proc R Soc Med. 1970 Sep;63(9):899-902. doi: 10.1177/003591577006300917.
2
The peritoneal exudate lymphocyte. I. Differences in antigen responsiveness between peritoneal exudate and lymph node lymphocytes from immunized guinea pigs.腹膜渗出淋巴细胞。I. 免疫豚鼠腹膜渗出淋巴细胞与淋巴结淋巴细胞抗原反应性的差异。
J Exp Med. 1971 Nov 1;134(5):1170-86. doi: 10.1084/jem.134.5.1170.
3
The mechanism of action of soluble lymphocytic mediators. I. A pulse exposure test for the measurement of macrophage migration inhibitory factor.可溶性淋巴细胞介质的作用机制。I. 用于测量巨噬细胞移动抑制因子的脉冲暴露试验。
Immunology. 1973 Jun;24(6):1027-34.
4
Lymphokine activity in vivo in relation to circulating monocyte levels and delayed skin reactivity.体内淋巴因子活性与循环单核细胞水平及皮肤迟发型反应的关系。
J Immunol. 1974 Apr;112(4):1540-7.
5
Mechanism of action of migration inhibitory factor (MIF). I. Evidence for a receptor for MIF present on the peritoneal macrophage but not on the alveolar macrophage.迁移抑制因子（MIF）的作用机制。I. 腹膜巨噬细胞存在MIF受体而肺泡巨噬细胞不存在该受体的证据。
J Exp Med. 1972 Sep 1;136(3):589-603. doi: 10.1084/jem.136.3.589.
6
Activity of migration inhibitory factor in the absence of antigen.
J Immunol. 1972 Aug;109(2):201-6.
7
Role of lymphocyte activation products (LAP) in cell-mediated immunity. I. Preparation and partial purification of guinea-pig LAP.淋巴细胞激活产物（LAP）在细胞介导免疫中的作用。I. 豚鼠LAP的制备及部分纯化
Clin Exp Immunol. 1972 Jan;10(1):25-47.
8
Studies on migration inhibitory factor (MIF): recovery of MIF activity after purification by gel filtration and disc electrophoresis.迁移抑制因子（MIF）的研究：通过凝胶过滤和圆盘电泳纯化后MIF活性的恢复。
Cell Immunol. 1970 May;1(1):133-45. doi: 10.1016/0008-8749(70)90066-3.
9
Studies on delayed hypersensitivity pleural exudates in guinea pigs. I. Demonstration of substances in the cell-free exudate which cause inhibition of mononuclear cell migration in vitro.豚鼠迟发型超敏反应性胸腔渗出液的研究。I. 无细胞渗出液中引起体外单核细胞迁移抑制的物质的证实。
Immunology. 1976 Apr;30(4):505-11.

腹腔中迁移抑制活性的存在与产生。

Presence and production of migration inhibitory activity in the peritoneal cavity.

作者信息

Van Maarsseveen A C

出版信息

Immunology. 1977 Jun;32(6):893-8.

PMID:328384
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1445459/
Abstract

The presence of migration inhibitory (MI) activity was investigated in the delayed hypersensitivity (DH) reaction induced by i.p. injection of PPD into FCA-sensitized guinea-pigs. Peritoneal exudates were studied at several times before and after the induction of the DH reaction and a non-immune control inflammation. Lymphokine (LK) fractions were prepared from individual exudates and tested in a conventional macrophage migration inhibition assay at concentrations determined to occur in vivo. The results suggest a continuous local production of MI activity and an augmented production during development of a DH reaction.

摘要

通过腹腔注射结核菌素纯蛋白衍生物（PPD）至弗氏完全佐剂（FCA）致敏的豚鼠体内诱导迟发型超敏反应（DH），研究其中迁移抑制（MI）活性的存在情况。在诱导DH反应和非免疫对照炎症之前及之后的多个时间点对腹腔渗出液进行研究。从各个渗出液中制备淋巴细胞因子（LK）组分，并在传统的巨噬细胞迁移抑制试验中，以体内测定的浓度进行检测。结果表明MI活性存在持续的局部产生，且在DH反应发展过程中产生增加。