免疫功能低下患者的传染病考虑因素。
Infectious disease considerations in immunocompromised patients.
机构信息
Bridget McGrath is director of hospitalist NP/PA service lines and a hospitalist PA at University of Chicago (Ill.) Medicine. Mary Broadhurst practices in infectious disease at St. Vincent Medical Group in Indianapolis, Ind. Christopher Roman is an associate professor at Butler University in Indianapolis. The authors have disclosed no potential conflicts of interest, financial or otherwise.
出版信息
JAAPA. 2020 Sep;33(9):16-25. doi: 10.1097/01.JAA.0000694948.01963.f4.
Immunocompromised patients account for about 3% of the US population. Complications arising from infection are common in these patients and can present diagnostic and therapeutic challenges. This article describes the pathophysiology of immunosuppression in five common immunocompromised states-asplenia, HIV infection, solid organ transplant, biologic use, and cancer-as well as specific infectious risks and considerations for affected patients and how to manage them.
免疫功能低下的患者约占美国总人口的 3%。这些患者中，感染引起的并发症很常见，可能给诊断和治疗带来挑战。本文描述了五种常见免疫功能低下状态（脾切除、HIV 感染、实体器官移植、生物制剂使用和癌症）中的免疫抑制病理生理学，以及对受影响患者的具体感染风险和注意事项，以及如何对其进行管理。
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