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双相情感障碍患者的生活质量

Quality of Life among Patients with Bipolar Disorder.

作者信息

Islam M K, Islam M S, Kibria S M, Rahman M M, Algin S, Mullick M S

机构信息

Dr Md Khayrul Islam, Assistant Professor, Department of Psychiatry, Tairunnesa Memorial Medical College, Gazipur, Bangladesh; E-mail:

出版信息

Mymensingh Med J. 2020 Jul;29(3):601-608.

PMID:32844800
Abstract

Bipolar Disorder is a major psychiatric disorder. It has a chronic course of remitting and relapsing episodes of mania and depression and tends to deteriorate mental and cognitive functions of patients. This disorder affects deeply the function and feelings of subjects and impacts negatively on quality of life. We found out the quality of life in patients with Bipolar Disorder with that of general population and order of impairment among domain of physical health, psychological health, social relationship and environment domain. This was a descriptive, cross-sectional, comparative and analytical study. The study was conducted in the department of Psychiatry, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh from January 2015 to October 2016. Eighty (80) patients with Bipolar Disorder who fulfilled inclusion criteria were selected as sample from department of psychiatry in BSMMU and National Institute of Mental Health, Dhaka. Clinical diagnosis of patients was done by consultant psychiatrist with Structured Clinical Interview for DSM-IV Axis I Disorders (SCID-I CV). Then Bengali version of WHO Quality of Life Scale brief version (WHOQOL BREF 1998) was applied to evaluate quality of life in different domains including physical health, psychological health, social relationship and environment domain. Semi structural questionnaire were used for collecting sociodemographic information. In this process of study age and sex matched 80 healthy controls from hospital staff and patient's attendants without physical or psychiatric illness were recruited for comparison. Data were analyzed by Statistical Package for Social Science Version 16. The study revealed that mean score of overall quality of life of patients were 3.11 and healthy controls were 3.95, mean score of overall health of patients were 2.94 and healthy control were 3.88, mean score of physical health domain of patients were 3.14 and healthy control were 4.00, mean score of psychological domain of patients were 3.01 and healthy control were 3.87, mean score of social relationship domain of patients were 2.31 and healthy control were 3.72, mean score of environment domain of patients were 2.73 and healthy control were 3.35. Among patients quality of life showed impaired in low socio-economic condition. Result of this study may help to encourage further research.

摘要

双相情感障碍是一种主要的精神疾病。它具有躁狂和抑郁发作缓解与复发的慢性病程,且往往会使患者的心理和认知功能恶化。这种疾病深刻影响个体的功能和感受,并对生活质量产生负面影响。我们比较了双相情感障碍患者与普通人群的生活质量,以及在身体健康、心理健康、社会关系和环境领域的损害程度顺序。这是一项描述性、横断面、比较性和分析性研究。该研究于2015年1月至2016年10月在孟加拉国达卡的班加班杜·谢赫·穆吉布医科大学(BSMMU)精神病学系进行。从BSMMU精神病学系和达卡国家心理健康研究所选取了80名符合纳入标准的双相情感障碍患者作为样本。患者的临床诊断由顾问精神科医生通过《精神疾病诊断与统计手册》第四版轴I障碍结构化临床访谈(SCID-I CV)进行。然后应用孟加拉语版的世界卫生组织生活质量量表简表(WHOQOL BREF 1998)来评估不同领域的生活质量,包括身体健康、心理健康、社会关系和环境领域。使用半结构化问卷收集社会人口学信息。在研究过程中,从医院工作人员和患者家属中招募了80名年龄和性别匹配、无身体或精神疾病的健康对照者进行比较。数据采用社会科学统计软件包第16版进行分析。研究显示,患者总体生活质量的平均得分是3.11,健康对照者为3.95;患者总体健康的平均得分是2.94,健康对照者为3.88;患者身体健康领域的平均得分是3.14,健康对照者为4.00;患者心理领域的平均得分是3.01,健康对照者为3.87;患者社会关系领域的平均得分是2.31,健康对照者为3.72;患者环境领域的平均得分是2.73,健康对照者为3.35。在患者中,低社会经济状况下生活质量受损。本研究结果可能有助于鼓励进一步的研究。

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