骨母细胞样分化型化生性乳腺癌的影像学特征。
Imaging characteristics of metaplastic breast cancer with osteoblastic differentiation.
机构信息
Charles E Schmidt College of Medicine, Florida Atlantic University, Boca Raton, Florida, USA
Department of Breast Imaging, Lynn Women's Health and Wellness Institute, Boca Raton, Florida, USA.
出版信息
BMJ Case Rep. 2020 Aug 26;13(8):e235050. doi: 10.1136/bcr-2020-235050.
An 82-year-old female presented to her breast surgeon with a hard, painful mass in the left breast. Mammography demonstrated a new hyperdense mass with pleomorphic calcifications of trabeculated appearance. Ultrasound-guided biopsy demonstrated a hypoechoic mass with significantly increased vascularity and tissue stiffness as well as additional irregular, hypoechoic masses in the same area. Together these findings suggested multifocal malignancy. The pathology report from the biopsy demonstrated fragments of solid sheets of epithelioid and focally spindled cells with multinucleated osteoclast giant cells. This was found to be most consistent with metaplastic carcinoma showing osteoblastic differentiation. The patient received a left-sided mastectomy. During follow-up with the patient, adjuvant chemotherapy was not advised given the relatively unknown survival advantage in this elderly patient.
一位 82 岁女性因左乳硬块伴触痛就诊于乳腺外科医生。乳腺 X 线摄影显示新的高密度肿块，伴有分叶状不规则钙化。超声引导下活检显示低回声肿块，血管丰富，组织僵硬，同一区域还有其他不规则低回声肿块。这些发现提示多灶性恶性肿瘤。活检的病理报告显示，有上皮样和局灶性梭形细胞的实性片状碎片，伴有多核破骨细胞巨细胞。这最符合具有成骨分化的化生性癌。患者接受了左侧乳房切除术。由于该老年患者的生存优势相对未知，因此在随访过程中不建议进行辅助化疗。
Zotero 插件