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一种主要外膜蛋白在大肠杆菌中的作用。

Role of a major outer membrane protein in Escherichia coli.

作者信息

Lutkenhaus J F

出版信息

J Bacteriol. 1977 Aug;131(2):631-7. doi: 10.1128/jb.131.2.631-637.1977.

DOI:10.1128/jb.131.2.631-637.1977
PMID:328491
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC235472/
Abstract

Mutants of Escherichia coli B/r lacking a major outer membrane protein, protein b, were obtained by selecting for resistance to copper. These mutants showed a decreased ability to utilize a variety of metabolites when the metabolites were present at low concentrations. Also, mutants of E. coli K-12 lacking proteins b and c from the outer membrane were shown to have an identical defect in the uptake of various metabolites. These results are discussed with regard to their implications as to the role of these proteins in permeability of the outer membrane,

摘要

通过筛选对铜的抗性，获得了缺乏主要外膜蛋白b的大肠杆菌B/r突变体。当代谢物浓度较低时，这些突变体利用多种代谢物的能力下降。此外，缺乏外膜蛋白b和c的大肠杆菌K-12突变体在摄取各种代谢物方面也表现出相同的缺陷。讨论了这些结果对这些蛋白质在外膜通透性中作用的影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7a60/235472/5d3ec15399f0/jbacter00303-0267-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7a60/235472/01da78865df6/jbacter00303-0264-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7a60/235472/a395e5aeff06/jbacter00303-0265-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7a60/235472/5d3ec15399f0/jbacter00303-0267-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7a60/235472/01da78865df6/jbacter00303-0264-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7a60/235472/a395e5aeff06/jbacter00303-0265-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7a60/235472/5d3ec15399f0/jbacter00303-0267-a.jpg

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本文引用的文献

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Characterization of the major envelope protein from Escherichia coli. Regular arrangement on the peptidoglycan and unusual dodecyl sulfate binding.大肠杆菌主要包膜蛋白的特性。在肽聚糖上的规则排列及与十二烷基硫酸盐的异常结合。
全基因组筛选揭示了肠杆菌素介导的铁摄取在铜胁迫下大肠杆菌生存中的作用。
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Use and treatment of chicken feathers as a natural adsorbent for the removal of copper in aqueous solution.将鸡毛用作天然吸附剂去除水溶液中铜的应用与处理
J Environ Health Sci Eng. 2021 Apr 14;19(1):707-720. doi: 10.1007/s40201-021-00639-4. eCollection 2021 Jun.
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Copper Homeostatic Mechanisms and Their Role in the Virulence of Escherichia coli and Salmonella enterica.铜稳态机制及其在大肠杆菌和沙门氏菌毒力中的作用。
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