Goldman E, McDonald J S, Peterson S S, Stock M C, Betts R, Frolicher D
Department of Anesthesiology, Ohio State University College of Medicine, Columbus 43210.
J Trauma. 1988 May;28(5):611-4. doi: 10.1097/00005373-198805000-00008.
Another study documented that percutaneous transtracheal ventilation with a special 3.5-mm I.D. cannula was possible in experimental complete upper airway obstruction (CAO) using Ambu-assisted ventilation. The effects of ventilation during CAO by occlusion of the endotracheal tube was evaluated by use of a portable oscillatory pressure device (POPD) attached to a 10-g (I.D. 2.4 mm) angiocath catheter inserted through the tracheal wall. Eight pigs were anesthetized and ventilated with the POPD for 15 minutes after CAO with a mean peak airway pressure of 14 cm H2O and continuous positive airway pressure of 5-7 cm H2O, tidal volume below 100 ml, and a rate below 0.5 Hz. A Venturi delivered an FIO2 of 0.68-0.92. All eight showed markedly stable blood gases and cardiovascular parameters (heart rate and systemic and pulmonary arterial pressures). A similar trend was obtained in a separate group of four pigs ventilated with an Ambu bag for 30 minutes; however, the PO2 was lower. In the control group, asphyxia after CAO produced cardiorespiratory failure in every animal in less than 6 minutes. Low-frequency ventilation with a POPD for CAO ensures adequate gas exchange using a standard transtracheal catheter of only 2.4 mm I.D.
另一项研究记录了在实验性完全上气道阻塞(CAO)中,使用特殊的内径3.5毫米套管进行经皮气管通气,并采用ambu辅助通气是可行的。通过使用连接到经气管壁插入的10克(内径2.4毫米)血管造影导管的便携式振荡压力装置(POPD),评估了在CAO期间通过阻塞气管导管进行通气的效果。八只猪麻醉后,在CAO后使用POPD通气15分钟,平均气道峰值压力为14厘米水柱,持续气道正压为5 - 7厘米水柱,潮气量低于100毫升,频率低于0.5赫兹。文丘里管输送的吸入氧分数为0.68 - 0.92。所有八只猪的血气和心血管参数(心率、体循环和肺动脉压)均显示出明显稳定。在另一组用ambu袋通气30分钟的四只猪中也得到了类似趋势;然而,动脉血氧分压较低。在对照组中,CAO后的窒息在不到6分钟内导致每只动物出现心肺衰竭。对于CAO,使用POPD进行低频通气可使用仅2.4毫米内径的标准气管导管确保充分的气体交换。