Department of Pediatrics, Albert Einstein College of Medicine.
Division of Pediatric Hematology, Oncology and Marrow & Blood Cell Transplantation, Children's Hospital at Montefiore, Bronx, NY.
J Pediatr Hematol Oncol. 2021 Aug 1;43(6):e859-e860. doi: 10.1097/MPH.0000000000001897.
The novel coronavirus, SARS-CoV-2, causes much more severe disease in adults than in children. Although it is anticipated that immune compromised children and children with cancer may be at higher risk of developing severe or fatal COVID-19, there are no currently published reports of fatal disease in a child with cancer. Because of the discrepancy in disease severity between adult and pediatric patients, we report the case of an adolescent with pulmonary metastatic osteosarcoma who died of COVID-19 early in the course of the pandemic in New York City in the hope that heightening awareness that pulmonary metastatic disease may predispose to a more severe outcome will increase surveillance in this vulnerable population.
新型冠状病毒（SARS-CoV-2）在成人中的致病性远高于儿童。尽管预计免疫功能低下的儿童和患有癌症的儿童发生重症或致死性 COVID-19 的风险更高，但目前尚无儿童癌症患者发生致死性疾病的报告。由于成人和儿科患者的疾病严重程度存在差异，我们报告了一例患有肺转移骨肉瘤的青少年患者的病例，该患者在纽约市大流行早期因 COVID-19 死亡。希望提高对肺转移疾病可能导致更严重后果的认识，从而增加对这一脆弱人群的监测。
