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多发性硬化症患者下肢健康研究:系统范围综述。

Research on lower extremity health in patients with multiple sclerosis: a systematic scoping review.

机构信息

Department of Nursing Science, University of Turku, 20014, Turku, Finland.

Turku University Hospital, Turku, Finland.

出版信息

J Foot Ankle Res. 2020 Aug 27;13(1):54. doi: 10.1186/s13047-020-00423-x.

DOI:10.1186/s13047-020-00423-x
PMID:32854741
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7457257/
Abstract

BACKGROUND

Multiple sclerosis (MS) often affects ambulation and the function of the lower limbs. However, little is known about how much research has been conducted on lower extremity health in patients with MS.

OBJECTIVE

To analyse empirical studies and their evidence on lower extremity health in patients with MS, in order to identify the need for future studies in key areas.

METHODS

A systematic scoping review was conducted. A literature search of Medline (PubMed), CINAHL (EBSCO) and the Cochrane Library databases was performed. The search covered the period up to 15 January 2020 from the earliest records available. This led to the inclusion of 42 empirical articles. The data were analysed using content analysis and quantification techniques.

RESULTS

The research on lower extremity health focused primarily on two main areas: gait and lower extremity muscle strength. Lower extremity health was assessed using a variety of methods, most of which consisted of objective physical tests and gait analysis. Patients with MS had many problems with the health of their lower extremities, which manifested in walking difficulties, balance problems, muscle weaknesses and spasticity. In the feet, pes cavus, claw toes, oedema and altered foot sensation were common.

CONCLUSIONS

MS affects lower limb and foot health, and these problems can affect patients' daily lives. However, the extent of these problems is poorly understood, partly due to the dearth of research on lower limb and foot health. Therefore, further research is warranted in order to better understand the impact of MS on foot and lower limb health in everyday life.

摘要

背景

多发性硬化症(MS)常影响行动能力和下肢功能。然而,对于 MS 患者下肢健康的研究却知之甚少。

目的

分析 MS 患者下肢健康的实证研究及其证据,以确定在关键领域开展未来研究的必要性。

方法

进行了系统的范围综述。对 Medline(PubMed)、CINAHL(EBSCO)和 Cochrane 图书馆数据库进行了文献检索。检索时间截至 2020 年 1 月 15 日,从最早的可用记录开始。这导致纳入了 42 篇实证文章。使用内容分析和量化技术对数据进行分析。

结果

下肢健康研究主要集中在两个主要领域:步态和下肢肌肉力量。使用多种方法评估下肢健康,其中大多数方法包括客观的体格检查和步态分析。MS 患者下肢健康存在许多问题,表现为行走困难、平衡问题、肌肉无力和痉挛。在脚部,常见高弓足、爪形趾、水肿和足部感觉改变。

结论

MS 影响下肢和足部健康,这些问题会影响患者的日常生活。然而,这些问题的严重程度尚未得到充分了解,部分原因是对下肢和足部健康的研究不足。因此,需要进一步研究,以更好地了解 MS 对日常生活中足部和下肢健康的影响。

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Next Steps in Wearable Technology and Community Ambulation in Multiple Sclerosis.可穿戴技术在多发性硬化症中的应用及社区活动的下一步。
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The clinical- and cost-effectiveness of functional electrical stimulation and ankle-foot orthoses for foot drop in Multiple Sclerosis: a multicentre randomized trial.
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Diabet Med. 2019 Nov;36(11):1417-1423. doi: 10.1111/dme.13964. Epub 2019 May 3.
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Clin Geriatr Med. 2019 May;35(2):161-171. doi: 10.1016/j.cger.2018.12.001. Epub 2019 Mar 1.
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