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透皮双氯芬酸贴剂在正畸患者拔除前磨牙后作为镇痛药的疗效。

Efficacy of Transdermal Diclofenac Patch as an Analgesic Following Premolar Extractions in Orthodontic Patients.

作者信息

Talnia Sanjay, Fry Ramesh Ram, Sharma Atul, Patidar Dinesh Chand, Goyal Samta, Gandhi Geetanjali

机构信息

Lecturer, Department of Oral and Maxillofacial Surgery, Swami Devi Dyal Hospital and Dental College, Barwala, Panchkula, Haryana, India.

Department of Oral and Maxillofacial Surgery, Maharishi Markandeshwar College of Dental Sciences and Research, Ambala, Haryana, India.

出版信息

Ann Maxillofac Surg. 2020 Jan-Jun;10(1):37-41. doi: 10.4103/ams.ams_220_18. Epub 2020 Jun 8.

Abstract

AIM

The aim of the study was to evaluate the efficacy of transdermal diclofenac patch versus oral diclofenac tablet as analgesic following premolar extractions in orthodontic patients.

MATERIALS AND METHODS

Thirty-three symmetrical pairs of indicated premolars (either first or second) were included for the present study. Each patient was given either transdermal diclofenac sodium patch 100 mg once a day or oral diclofenac tablet 50 mg twice a day for 3 days after the extraction. Pain was assessed by a 10-point visual analog scale and 4-point verbal rating scale given to the patient for each day for 3 days after the extraction. All observational findings were recorded, tabulated, and analyzed statistically.

RESULTS

This study consisted of 33 patients with a mean age of 18.73 ± 3.677 years. Out of 33 patients included in this study, 5 were male and 28 were female. The result of the study showed that consecutive postoperative days transdermal diclofenac patch was slightly more efficient in controlling the postoperative pain in the extraction done for the orthodontic purpose than diclofenac oral tablet, however statistically no significant difference was observed using Chi-square test ( > 0.05).

CONCLUSION

Transdermal diclofenac patch showed potential analgesic modality for the management of mild-to-moderate intensity pain in premolar orthodontic extraction, with lower incidence of systemic adverse effects. However, cost and availability may limit the use of transdermal patch.

摘要

目的

本研究旨在评估正畸患者拔除前磨牙后,透皮双氯芬酸贴片与口服双氯芬酸片剂作为镇痛药的疗效。

材料与方法

本研究纳入33对对称的指定前磨牙(第一或第二前磨牙)。每位患者在拔牙后3天,每天接受一次100mg透皮双氯芬酸钠贴片或每天两次50mg口服双氯芬酸片剂治疗。拔牙后3天,每天通过10分视觉模拟量表和4分语言评定量表对患者的疼痛进行评估。记录所有观察结果,列表并进行统计学分析。

结果

本研究包括33名患者,平均年龄为18.73±3.677岁。在纳入本研究的33名患者中,男性5名,女性28名。研究结果表明,对于正畸目的拔牙术后疼痛的控制,连续术后几天透皮双氯芬酸贴片比双氯芬酸口服片剂略有效,但使用卡方检验未观察到统计学显著差异(>0.05)。

结论

透皮双氯芬酸贴片显示出在正畸前磨牙拔除术中管理轻至中度疼痛的潜在镇痛方式,全身不良反应发生率较低。然而,成本和可获得性可能会限制透皮贴片的使用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/26fb/7433980/4f658a950512/AMS-10-37-g001.jpg

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