Role of autophagy in drug induced liver injury.
作者信息
Brecklinghaus Tim
机构信息
Leibniz Research Centre for Working Environment and Human Factors, Ardeystr. 67, 44139, Dortmund, Germany.
出版信息
Arch Toxicol. 2020 Oct;94(10):3599-3600. doi: 10.1007/s00204-020-02887-z. Epub 2020 Aug 27.
Abstract
摘要
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Arch Toxicol. 2020 Oct;94(10):3599-3600. doi: 10.1007/s00204-020-02887-z. Epub 2020 Aug 27.
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[Amiodarone-induced liver dysfunctions].[胺碘酮所致肝功能障碍]
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[Amiodarone and liver damage].[胺碘酮与肝损伤]
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[Digitalis intoxication in the presence of amiodarone-induced acute hepatitis].胺碘酮诱发急性肝炎时的洋地黄中毒
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7
Acute amiodarone-induced hepatitis.急性胺碘酮诱发的肝炎。
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Amiodarone-induced liver toxicity.胺碘酮所致肝毒性。
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How toxic is amiodarone to the liver?胺碘酮对肝脏的毒性有多大？
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Autophagy alleviates amiodarone-induced hepatotoxicity.自噬可减轻胺碘酮诱导的肝毒性。
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Prediction of human drug-induced liver injury (DILI) in relation to oral doses and blood concentrations.预测与口服剂量和血液浓度相关的人体药物性肝损伤（DILI）。
Arch Toxicol. 2019 Jun;93(6):1609-1637. doi: 10.1007/s00204-019-02492-9. Epub 2019 Jun 27.
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Toxicogenomics directory of rat hepatotoxicants in vivo and in cultivated hepatocytes.大鼠在体和原代肝细胞肝毒物毒理学基因组目录。
Arch Toxicol. 2018 Dec;92(12):3517-3533. doi: 10.1007/s00204-018-2352-3. Epub 2018 Dec 3.
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Relevance of the incubation period in cytotoxicity testing with primary human hepatocytes.原代人肝细胞细胞毒性试验中潜伏期的相关性。
Arch Toxicol. 2018 Dec;92(12):3505-3515. doi: 10.1007/s00204-018-2302-0. Epub 2018 Oct 13.
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Bile Microinfarcts in Cholestasis Are Initiated by Rupture of the Apical Hepatocyte Membrane and Cause Shunting of Bile to Sinusoidal Blood.胆汁微梗死在胆汁淤积中是由肝细胞顶膜破裂引发的，并导致胆汁分流到窦状隙血液。
Hepatology. 2019 Feb;69(2):666-683. doi: 10.1002/hep.30213. Epub 2018 Nov 19.
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Adverse outcome pathways: opportunities, limitations and open questions.不良结局途径：机遇、局限性和未解决问题。
Arch Toxicol. 2017 Nov;91(11):3477-3505. doi: 10.1007/s00204-017-2045-3. Epub 2017 Oct 19.
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In vivo imaging of systemic transport and elimination of xenobiotics and endogenous molecules in mice.小鼠体内异生物素和内源性分子的全身转运与消除的活体成像
Arch Toxicol. 2017 Mar;91(3):1335-1352. doi: 10.1007/s00204-016-1906-5. Epub 2016 Dec 20.
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The ascending pathophysiology of cholestatic liver disease.胆汁淤积性肝病的上行发病机制。
Hepatology. 2017 Feb;65(2):722-738. doi: 10.1002/hep.28965.
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Model-guided identification of a therapeutic strategy to reduce hyperammonemia in liver diseases.基于模型指导的治疗策略鉴定，以降低肝脏疾病中的血氨过多症。
J Hepatol. 2016 Apr;64(4):860-71. doi: 10.1016/j.jhep.2015.11.018. Epub 2015 Nov 27.
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Cholestasis-induced adaptive remodeling of interlobular bile ducts.胆汁淤积诱导的小叶间胆管适应性重塑。
Hepatology. 2016 Mar;63(3):951-64. doi: 10.1002/hep.28373. Epub 2016 Jan 14.
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