Schröfel Adam, Kratošová Gabriela, Šafařík Ivo, Šafaříková Mirka, Raška Ivan, Shor Leslie M
Department of Nanobiotechnology, Institute of Nanobiology and Structural Biology of GCRC, Academy of Sciences, Ceske Budejovice, Czech Republic; Department of Chemical and Biomolecular Engineering, University of Connecticut, Storrs, CT, USA; Charles University, Institute of Cellular Biology and Pathology, Prague, Czech Republic.
Nanotechnology Centre, VSB-Technical University in Ostrava, Ostrava, Czech Republic.
Acta Biomater. 2014 Oct;10(10):4023-42. doi: 10.1016/j.actbio.2014.05.022. Epub 2014 Jun 9.
We present a comprehensive review of the applications of biosynthesized metallic nanoparticles (NPs). The biosynthesis of metallic NPs is the subject of a number of recent reviews, which focus on the various "bottom-up" biofabrication methods and characterization of the final products. Numerous applications exploit the advantages of biosynthesis over chemical or physical NP syntheses, including lower capital and operating expenses, reduced environmental impacts, and superior biocompatibility and stability of the NP products. The key applications reviewed here include biomedical applications, especially antimicrobial applications, but also imaging applications, catalytic applications such as reduction of environmental contaminants, and electrochemical applications including sensing. The discussion of each application is augmented with a critical review of the potential for continued development.
我们对生物合成金属纳米颗粒（NPs）的应用进行了全面综述。金属纳米颗粒的生物合成是近期一些综述的主题，这些综述聚焦于各种“自下而上”的生物制造方法以及最终产物的表征。众多应用利用了生物合成相较于化学或物理纳米颗粒合成的优势，包括更低的资本和运营成本、减少的环境影响以及纳米颗粒产品卓越的生物相容性和稳定性。这里综述的关键应用包括生物医学应用，尤其是抗菌应用，还有成像应用、催化应用（如还原环境污染物）以及电化学应用（包括传感）。对每个应用的讨论都辅以对持续发展潜力的批判性综述。
