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一种用于检测初次全髋关节或全膝关节置换术后深部手术部位感染的半自动监测算法的验证:一项多中心研究。

Validation of an algorithm for semiautomated surveillance to detect deep surgical site infections after primary total hip or knee arthroplasty-A multicenter study.

机构信息

Department of Medical Microbiology and Infection Prevention, University Medical Center Utrecht, Utrecht, The Netherlands.

Department of Epidemiology and Surveillance, Center for Infectious Disease Control, National Institute for Public Health and the Environment, Bilthoven, The Netherlands.

出版信息

Infect Control Hosp Epidemiol. 2021 Jan;42(1):69-74. doi: 10.1017/ice.2020.377. Epub 2020 Aug 28.

DOI:10.1017/ice.2020.377
PMID:32856575
Abstract

OBJECTIVE

Surveillance of healthcare-associated infections is often performed by manual chart review. Semiautomated surveillance may substantially reduce workload and subjective data interpretation. We assessed the validity of a previously published algorithm for semiautomated surveillance of deep surgical site infections (SSIs) after total hip arthroplasty (THA) or total knee arthroplasty (TKA) in Dutch hospitals. In addition, we explored the ability of a hospital to automatically select the patients under surveillance.

DESIGN

Multicenter retrospective cohort study.

METHODS

Hospitals identified patients who underwent THA or TKA either by procedure codes or by conventional surveillance. For these patients, routine care data regarding microbiology results, antibiotics, (re)admissions, and surgeries within 120 days following THA or TKA were extracted from electronic health records. Patient selection was compared with conventional surveillance and patients were retrospectively classified as low or high probability of having developed deep SSI by the algorithm. Sensitivity, positive predictive value (PPV), and workload reduction were calculated and compared to conventional surveillance.

RESULTS

Of 9,554 extracted THA and TKA surgeries, 1,175 (12.3%) were revisions, and 8,378 primary surgeries remained for algorithm validation (95 deep SSIs, 1.1%). Sensitivity ranged from 93.6% to 100% and PPV ranged from 55.8% to 72.2%. Workload was reduced by ≥98%. Also, 2 SSIs (2.1%) missed by the algorithm were explained by flaws in data selection.

CONCLUSIONS

This algorithm reliably detects patients with a high probability of having developed deep SSI after THA or TKA in Dutch hospitals. Our results provide essential information for successful implementation of semiautomated surveillance for deep SSIs after THA or TKA.

摘要

目的

医疗保健相关性感染的监测通常通过人工图表审查来进行。半自动化监测可以大大减少工作量和主观数据解释。我们评估了先前发表的一种用于荷兰医院髋关节置换术(THA)或膝关节置换术(TKA)后深部手术部位感染(SSI)半自动化监测的算法的有效性。此外,我们还探讨了医院自动选择监测患者的能力。

设计

多中心回顾性队列研究。

方法

医院通过手术代码或常规监测来识别接受 THA 或 TKA 的患者。对于这些患者,从电子健康记录中提取了 120 天内与微生物学结果、抗生素、(再)入院和手术有关的常规护理数据。将患者选择与常规监测进行比较,并通过算法将患者回溯性地分为低或高发生深部 SSI 的可能性。计算了敏感性、阳性预测值(PPV)和工作量减少,并与常规监测进行了比较。

结果

从提取的 9554 例 THA 和 TKA 手术中,1175 例(12.3%)为翻修手术,8378 例为原发性手术,用于算法验证(95 例深部 SSI,1.1%)。敏感性范围为 93.6%至 100%,PPV 范围为 55.8%至 72.2%。工作量减少了≥98%。此外,算法漏报的 2 例 SSI(2.1%)可归因于数据选择中的缺陷。

结论

该算法可可靠地检测出荷兰医院中 THA 或 TKA 后发生深部 SSI 可能性较高的患者。我们的结果为成功实施 THA 或 TKA 后深部 SSI 的半自动化监测提供了重要信息。

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