Trzepacz P T, Brenner R P, Coffman G, van Thiel D H
Department of Psychiatry, University of Pittsburgh, School of Medicine, PA.
Biol Psychiatry. 1988 May;24(1):3-14. doi: 10.1016/0006-3223(88)90116-3.
We report the results of electroencephalograms, Mini-Mental State exam, Trailmaking Tests A and B, and serum albumin levels in 108 consecutive liver transplantation candidates. We compared test results to a clinical DSM-III diagnosis of delirium. Although each variable could differentiate between the two groups (delirium n = 18; nondelirium n = 90) at a statistically significant level, a discriminant analysis involving either all variables or only three particular variables (Trailmaking B, EEG code, and albumin) resulted in the highest specificity (97.8%) and sensitivity (83.3%), with a correct classification of 95.4% of subjects. The analysis also generates an equation that can be applied to clinical situations to enhance the accurate recognition of delirium. In addition, to explain abnormal Trailmaking B scores and/or EEGs in subjects who did not otherwise meet DSM-III criteria for delirium, we suggest the presence of a "subclinical delirium."
我们报告了108例连续的肝移植候选者的脑电图、简易精神状态检查、A和B型连线测试结果以及血清白蛋白水平。我们将测试结果与谵妄的临床DSM-III诊断进行了比较。尽管每个变量在统计学显著水平上都能区分两组（谵妄组n = 18；非谵妄组n = 90），但涉及所有变量或仅三个特定变量（B型连线测试、脑电图编码和白蛋白）的判别分析产生了最高的特异性（97.8%）和敏感性（83.3%），对95.4%的受试者进行了正确分类。该分析还生成了一个可应用于临床情况以提高谵妄准确识别率的方程。此外，为了解释未达到DSM-III谵妄标准的受试者中异常的B型连线测试分数和/或脑电图，我们提出存在“亚临床谵妄”。
