Department of Community Nutrition, School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences (TUMS), Tehran, Iran.
Department of Urology, Sina Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Clin Nutr ESPEN. 2020 Oct;39:173-179. doi: 10.1016/j.clnesp.2020.06.021. Epub 2020 Jul 24.
The relation of the Dietary Approaches to Stop Hypertension (DASH)-style diet to urinary lithogenic factors is unclear. This study aimed to assess the association between adherence to the DASH diet and urinary risk factors of kidney stones formation.
A total of 264 men apparently with nephrolithiasis, aged 18-89 years, participated in this cross-sectional study. The food item-based DASH diet based on 8 components (nuts and legumes, red and processed meat, low-fat dairy products, sweetened beverages, fruits, vegetables, sodium, and whole grains) and nutrient-based DASH score based on 9 target nutrients (protein, fiber, total fat, saturated fat, cholesterol, sodium, calcium, potassium, and magnesium) were calculated using a food frequency questionnaire. Urine analysis was performed to measure hypercalciuria, hypocitraturia, hyperoxaluria, hyperuricosuria, and hypercreatinuria as study outcomes. Multivariate logistic regression analysis was used to evaluate the relation of DASH diet to urinary factors.
After multivariate adjustment, high adherence to the food-based or nutrient-based DASH dietary patterns was significantly associated with lower odds for hypercreatininuria, hypocitraturia, and hypercalciuria. Higher nutrient-based DASH diet scores were related to lower odds of hyperuricosuria and moderate adherence to the food-based DASH score increased odds for hyperoxaluria. Moreover, expect for "Nuts and legumes" and sodium, other components of DASH diet were significantly related to urinary lithogenic factors.
Adherence to the DASH diet may be a strong preventive approach to decrease urinary risk factors of kidney stone formation.
“得舒饮食法”（DASH）与尿结石形成的相关结石形成风险因素之间的关系尚不清楚。本研究旨在评估 DASH 饮食与尿结石形成的相关风险因素之间的关系。
共有 264 名年龄在 18-89 岁的疑似肾结石男性参与了这项横断面研究。采用基于 8 种食物成分（坚果和豆类、红色和加工肉类、低脂乳制品、含糖饮料、水果、蔬菜、钠和全谷物）的食物频率问卷计算基于食物的 DASH 饮食和基于 9 种目标营养素（蛋白质、纤维、总脂肪、饱和脂肪、胆固醇、钠、钙、钾和镁）的 DASH 评分。通过尿液分析测量高钙尿症、低柠檬酸尿症、高草酸尿症、高尿酸尿症和高肌氨酸尿症作为研究结果。采用多变量 logistic 回归分析评估 DASH 饮食与尿液因素的关系。
在进行多变量调整后，高依从性的基于食物或基于营养素的 DASH 饮食模式与较低的发生高肌氨酸尿症、低柠檬酸尿症和高钙尿症的几率显著相关。较高的基于营养素的 DASH 饮食评分与较低的高尿酸尿症几率相关，而中等程度的基于食物的 DASH 评分增加与较高的高草酸尿症几率相关。此外，除了“坚果和豆类”和钠之外，DASH 饮食的其他成分与尿结石形成的风险因素显著相关。
遵循 DASH 饮食可能是降低尿结石形成风险因素的强有力预防方法。
