Division of Urology, Department of Surgery, University of Toronto, Toronto, Ontario, Canada.
Can J Urol. 2020 Aug;27(4):10322-10328.
Urethral stricture disease can be difficult to treat and stricture recurrence is common. The management of stricture disease has evolved and urethroplasty can achieve a high rate of lasting urethral patency. Nevertheless, endoscopic treatments still seem to have sub-optimal outcomes with high stricture recurrence rates. The Optilume drug-coated balloon represents a step forward in the endoscopic management of urethral strictures. The drug-coated balloon may offer an intermediate step prior to repeated dilations, urethrostomies, or urethroplasty. This treatment modality is a promising alternative to current endoscopic management and an option for patients that are poor surgical candidates or decline urethroplasty.
尿道狭窄疾病的治疗较为困难,且狭窄易复发。尿道狭窄的治疗方法已经有所发展,尿道成形术可实现较高的尿道通畅率。然而,内镜治疗的效果似乎仍不理想,狭窄复发率较高。Optilume 药物涂层球囊在尿道狭窄的内镜治疗方面是一个进步。药物涂层球囊可能是在重复扩张、尿道造口术或尿道成形术之前的一个中间步骤。这种治疗方式是目前内镜治疗的一种有前途的替代方法,也是手术效果差或拒绝尿道成形术的患者的一种选择。