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全身溶栓作为COVID-19相关急性主髂动脉和下肢动脉血栓形成的初始治疗方法

Systemic Thrombolysis as Initial Treatment of COVID-19 Associated Acute Aortoiliac and Lower Extremity Arterial Thrombosis.

作者信息

Patel Priya, Yu Yasong, Zia Saqib, Padberg Frank, Curi Michael, Huang Joe

机构信息

Division of Vascular Surgery, Rutgers University, New Jersey Medical School, Newark, NJ.

Division of Vascular Surgery, Rutgers University, New Jersey Medical School, Newark, NJ.

出版信息

Ann Vasc Surg. 2021 Jan;70:297-301. doi: 10.1016/j.avsg.2020.08.083. Epub 2020 Aug 28.

Abstract

SARS-CoV-2 (COVID-19) patients with associated thromboembolic events have demonstrated poor outcomes despite the use of anticoagulation therapy and surgical intervention. We present a COVID-19 patient with acute limb ischemia, secondary to extensive thrombosis of an aortic aneurysm, iliac arteries, and infrainguinal arteries. Initial treatment with systemic thrombolysis, which restored patency of the aortoiliac occlusion, was followed by open thrombectomies of the infrainguinal occlusions.

摘要

尽管使用了抗凝治疗和手术干预,但伴有血栓栓塞事件的严重急性呼吸综合征冠状病毒2(SARS-CoV-2,即新型冠状病毒肺炎)患者的预后仍然较差。我们报告了一名新型冠状病毒肺炎患者,其因主动脉瘤、髂动脉和腹股沟下动脉广泛血栓形成继发急性肢体缺血。最初采用全身溶栓治疗,恢复了主髂动脉闭塞的通畅,随后对腹股沟下闭塞进行了切开取栓术。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6411/7453212/61038ba6ef34/gr1_lrg.jpg

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