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COVID-19 与外周动脉血栓形成:小型综述。

COVID-19 and Peripheral Artery Thrombosis: A Mini Review.

机构信息

Cardiovascular Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Students' Scientific Research Center (SSRC), Tehran University of Medical Sciences, Tehran, Iran.

出版信息

Curr Probl Cardiol. 2022 Oct;47(10):100992. doi: 10.1016/j.cpcardiol.2021.100992. Epub 2021 Sep 24.

Abstract

For more than 2 years, health care systems have been floundering in a massive crisis of coronavirus disease 2019 (COVID-19) pandemic. While acute respiratory distress syndrome is the main complication in patients with COVID-19, as the pandemic continues, more data about the nonrespiratory effects of the coronavirus is obtained, including developing Coagulopathy-related manifestations, in the form of venous and arterial thromboembolism. Although arterial thrombosis a rare complication of this disease, it proves to be an effective factor in the mortality and morbidity of COVID-19 patients. The pathophysiology of thrombosis reveals a complex relation between hemostasis and immune system that can be disrupted by COVID-19. Thrombectomy, anticoagulant therapy, and thrombolysis are the main treatments in these patients. In addition, appropriate thromboprophylaxis treatment should be considered in COVID-19 patients. In this article, we have successfully reviewed the arterial thrombotic events in patients reported around the world, including the diagnostic and management method of choice.

摘要

两年来,医疗保健系统一直在 2019 冠状病毒病(COVID-19)大流行的巨大危机中苦苦挣扎。虽然急性呼吸窘迫综合征是 COVID-19 患者的主要并发症,但随着大流行的继续,关于冠状病毒非呼吸作用的更多数据被获得,包括以静脉和动脉血栓栓塞的形式出现的凝血功能障碍相关表现。尽管动脉血栓形成是这种疾病的罕见并发症,但它被证明是 COVID-19 患者死亡率和发病率的一个有效因素。血栓形成的病理生理学揭示了止血和免疫系统之间的复杂关系,COVID-19 可以破坏这种关系。取栓术、抗凝治疗和溶栓是这些患者的主要治疗方法。此外,COVID-19 患者应考虑适当的血栓预防治疗。在本文中,我们成功地回顾了世界各地报告的患者的动脉血栓性事件,包括首选的诊断和治疗方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0a97/8462005/6574cfa2ceef/gr1_lrg.jpg

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