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2007-2017 年荷兰关节置换登记处 201211 例初次水泥固定和非水泥固定全膝关节置换术的可比中期翻修率。

Comparable mid-term revision rates of primary cemented and cementless total knee arthroplasties in 201,211 cases in the Dutch Arthroplasty Register (2007-2017).

机构信息

Department of Orthopedic Surgery, HagaZiekenhuis, Sportlaan 600, 2566, The Hague, The Netherlands.

Department of Orthopedic Surgery, Langeland Ziekenhuis, Zoetermeer, The Netherlands.

出版信息

Knee Surg Sports Traumatol Arthrosc. 2021 Oct;29(10):3400-3408. doi: 10.1007/s00167-020-06183-2. Epub 2020 Aug 30.

Abstract

PURPOSE

Long-term failure of total knee arthroplasty (TKA) is mostly due to loosening of the prosthesis. In this study, the short- and mid-term revision rates of cemented vs cementless TKAs were investigated. Comparable short- and mid-term survival rates of both fixation methods were expected.

METHODS

Data on all cemented and cementless TKAs performed between 2007 and 2017 were retrieved from the Dutch Arthroplasty Register. The cumulative crude incidence of revision of cemented and cementless TKA was calculated. Death was considered a competing risk. Revision rates were compared using multivariable Cox proportional hazard regression analysis. The associations between fixation method and type of revision or reason for revision were tested using logistic regression analyses.

RESULTS

In total, 190,651 (94.8%) cemented and 10,560 (5.3%) cementless TKAs were evaluated. Both groups had comparable case characteristics. Cemented TKAs were inserted more often in cases with previous knee surgery compared to cementless TKAs (32% vs 27%). The cumulative incidence of revision after 9 years was 5.5% (CI 5.3-5.6%) for cemented and 5.8% (CI 5.2-6.4%) for cementless TKAs (p = 0.2). Cementless TKAs were more often revised due to loosening of the tibial (27% vs 18%; p < 0.001) or the femoral component (7% vs 5%; p = 0.005) than cemented TKAs. Cemented TKAs were more often revised due to infection (17% vs 9%; p = 0.004) than cementless TKAs.

CONCLUSION

In conclusion, cemented and cementless TKAs have comparable short- and mid-term revision rates based on a nationwide register study.

LEVEL OF EVIDENCE

III.

摘要

目的

全膝关节置换术(TKA)的长期失败主要归因于假体松动。本研究旨在调查骨水泥固定与非骨水泥固定 TKA 的短期和中期翻修率。预计两种固定方法的短期和中期生存率相当。

方法

从荷兰关节置换登记处检索了 2007 年至 2017 年间所有行骨水泥固定和非骨水泥固定 TKA 的数据。计算了骨水泥固定和非骨水泥固定 TKA 的累计粗翻修率。死亡被视为竞争风险。使用多变量 Cox 比例风险回归分析比较翻修率。使用逻辑回归分析测试固定方法与翻修类型或翻修原因之间的关联。

结果

共评估了 190651 例(94.8%)骨水泥固定和 10560 例(5.3%)非骨水泥固定 TKA。两组患者的病例特征具有可比性。与非骨水泥固定 TKA 相比,骨水泥固定 TKA 更常应用于既往膝关节手术病例(32%比 27%)。9 年后的累计翻修率为骨水泥固定组 5.5%(95%CI:5.3%-5.6%),非骨水泥固定组 5.8%(95%CI:5.2%-6.4%)(p=0.2)。非骨水泥固定 TKA 因胫骨(27%比 18%;p<0.001)或股骨组件(7%比 5%;p=0.005)松动而翻修的比例高于骨水泥固定 TKA。骨水泥固定 TKA 因感染(17%比 9%;p=0.004)而翻修的比例高于非骨水泥固定 TKA。

结论

基于全国注册研究,骨水泥固定和非骨水泥固定 TKA 的短期和中期翻修率相当。

证据等级

III。

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