North Bristol Trust, Bristol, UK.
Newcastle University, Newcastle-upon-Tyne, UK.
Bone Joint J. 2020 Sep;102-B(9):1176-1182. doi: 10.1302/0301-620X.102B9.BJJ-2020-0203.R1.
The James Lind Alliance aims to bring patients, carers, and clinicians together to identify uncertainties regarding care. A Priority Setting Partnership was established by the British Association for Surgery of the Knee in conjunction with the James Lind Alliance to identify research priorities related to the assessment, management, and rehabilitation of patients with persistent symptoms after knee arthroplasty.
The project was conducted using the James Lind Alliance protocol. A steering group was convened including patients, surgeons, anaesthetists, nurses, physiotherapists, and researchers. Partner organizations were recruited. A survey was conducted on a national scale through which patients, carers, and healthcare professionals submitted key unanswered questions relating to problematic knee arthroplasties. These were analyzed, aggregated, and synthesized into summary questions and the relevant evidence was checked. After confirming that these were not answered in the current literature, 32 questions were taken forward to an interim prioritization survey. Data from this survey informed a shortlist taken to a final consensus meeting.
A total of 769 questions were received during the initial survey with national reach across the UK. These were refined into 32 unique questions by an independent information specialist. The interim prioritization survey was completed by 201 respondents and 25 questions were taken to a final consensus group meeting between patients, carers, and healthcare professionals. Consensus was reached for ranking the top ten questions for publication and dissemination.
The top ten research priorities focused on pain, infection, stiffness, health service configuration, surgical and non-surgical management strategies, and outcome measures. This list will guide funders and help focus research efforts within the knee arthroplasty community. Cite this article: 2020;102-B(9):1176-1182.
詹姆斯·林德联盟旨在将患者、护理人员和临床医生聚集在一起，以确定护理方面的不确定性。英国膝关节外科协会与詹姆斯·林德联盟合作成立了一个优先事项设定伙伴关系，以确定与膝关节置换术后持续性症状患者的评估、管理和康复相关的研究重点。
该项目采用詹姆斯·林德联盟方案进行。召集了一个指导小组，包括患者、外科医生、麻醉师、护士、物理治疗师和研究人员。招募了合作伙伴组织。通过全国范围的调查，患者、护理人员和医疗保健专业人员提交了与膝关节置换术相关的关键未解决问题，开展了项目。对这些问题进行了分析、汇总和综合成总结问题，并检查了相关证据。在确认这些问题在当前文献中没有得到回答后，将 32 个问题推进到中期优先排序调查。该调查的数据为最终共识会议提供了一个入围名单。
初始调查共收到 769 个问题，在英国全国范围内都有涉及。由独立信息专家将这些问题精炼成 32 个独特的问题。中期优先排序调查由 201 名受访者完成，25 个问题提交给了患者、护理人员和医疗保健专业人员之间的最终共识小组会议。达成共识，将排名前十的问题进行公布和传播。
排名前十的研究重点集中在疼痛、感染、僵硬、卫生服务配置、手术和非手术管理策略以及结果衡量标准上。这份清单将指导资助者，并帮助聚焦膝关节置换术领域的研究工作。 引用本文：2020；102-B（9）：1176-1182。
