Dept. of Chemical Engineering, Jashore University of Science and Technology, Jashore, 7408, Bangladesh; Laboratory of Nano-bio and Advanced Materials Engineering (NAME), Jashore University of Science and Technology, Jashore, 7408, Bangladesh.
Dept. of Chemical Engineering, Jashore University of Science and Technology, Jashore, 7408, Bangladesh; Institute of Nanoscience of Aragon, Department of Chemical Engineering and Environmental Technology, University of Zaragoza, Aragon, Spain.
Biosens Bioelectron. 2020 Oct 15;166:112431. doi: 10.1016/j.bios.2020.112431. Epub 2020 Jul 16.
Last few decades, viruses are a real menace to human safety. Therefore, the rapid identification of viruses should be one of the best ways to prevent an outbreak and important implications for medical healthcare. The recent outbreak of coronavirus disease (COVID-19) is an infectious disease caused by a newly discovered coronavirus which belongs to the single-stranded, positive-strand RNA viruses. The pandemic dimension spread of COVID-19 poses a severe threat to the health and lives of seven billion people worldwide. There is a growing urgency worldwide to establish a point-of-care device for the rapid detection of COVID-19 to prevent subsequent secondary spread. Therefore, the need for sensitive, selective, and rapid diagnostic devices plays a vital role in selecting appropriate treatments and to prevent the epidemics. During the last decade, electrochemical biosensors have emerged as reliable analytical devices and represent a new promising tool for the detection of different pathogenic viruses. This review summarizes the state of the art of different virus detection with currently available electrochemical detection methods. Moreover, this review discusses different fabrication techniques, detection principles, and applications of various virus biosensors. Future research also looks at the use of electrochemical biosensors regarding a potential detection kit for the rapid identification of the COVID-19.
过去几十年，病毒对人类安全构成了严重威胁。因此，快速识别病毒应该是预防疫情爆发的最佳方法之一，对医疗保健也有重要意义。最近爆发的冠状病毒病（COVID-19）是一种由新发现的冠状病毒引起的传染病，属于单链、正链 RNA 病毒。COVID-19 的大流行规模传播对全球 70 亿人的健康和生命构成了严重威胁。全球迫切需要建立一种即时检测设备，以快速检测 COVID-19，防止后续的二次传播。因此，对敏感、选择性和快速诊断设备的需求对于选择适当的治疗方法和预防疫情至关重要。在过去十年中，电化学生物传感器已成为可靠的分析设备，代表了一种用于检测不同致病性病毒的新的有前途的工具。本文综述了目前可用的电化学检测方法在不同病毒检测中的最新研究进展。此外，本文还讨论了各种病毒生物传感器的不同制造技术、检测原理和应用。未来的研究还着眼于电化学生物传感器在 COVID-19 快速识别方面的潜在检测试剂盒的应用。
