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用于快速检测食源性病原体的微流控生物传感器:最新进展与未来展望

Microfluidic biosensors for rapid detection of foodborne pathogenic bacteria: recent advances and future perspectives.

作者信息

Zhang Jian, Ma Chuanlong, Du Yaping, Huang Jiangbo, Xue Li

机构信息

School of Robot Engineering, Yangtze Normal University, Chongqing, China.

Department of Building Environment and Energy Engineering, The Hong Kong Polytechnic University, Hong Kong, China.

出版信息

Front Chem. 2025 Jan 29;13:1536928. doi: 10.3389/fchem.2025.1536928. eCollection 2025.

Abstract

Rapid detection of foodborne pathogenic bacteria is critical for ensuring food safety and preventing foodborne disease outbreaks. Traditional detection methods, while accurate, are often time-consuming and labor-intensive, making rapid detection technologies a pressing need. Microfluidic biosensors have emerged as a powerful solution, offering high sensitivity, specificity, and rapid analysis with minimal sample volume. In this review, we summarize recent advances in microfluidic biosensor technology, highlighting innovations in detection techniques such as electrochemical and optical microfluidic biosensors. We have also introduced microfluidic components, which are crucial for the implementation of microfluidic biosensors. Based on the current state of this technology development, we finally provide several most important recommendations for future research directions in this emerging research area, which may enable widespread commercialization and adoption in the food industry.

摘要

快速检测食源性病原体对于确保食品安全和预防食源性疾病爆发至关重要。传统检测方法虽然准确,但往往耗时且 labor-intensive,这使得快速检测技术成为迫切需求。微流控生物传感器已成为一种强大的解决方案,具有高灵敏度、特异性,且能以最小样本量进行快速分析。在本综述中,我们总结了微流控生物传感器技术的最新进展,突出了电化学和光学微流控生物传感器等检测技术的创新。我们还介绍了微流控组件,其对于微流控生物传感器的实现至关重要。基于该技术发展的现状,我们最终为这个新兴研究领域的未来研究方向提供了几条最重要的建议,这可能会促使其在食品工业中广泛商业化和应用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2a21/11815284/338eb5d7cd9f/fchem-13-1536928-g001.jpg

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