CeNDIE-ANLIS Carlos G. Malbrán, Av. Paseo Colón 568, C1063 Caba, Argentina.
Laboratorio MF Salvador, Rioja 2829, S2002OJM Rosario, Santa Fe, Argentina.
Vet Parasitol Reg Stud Reports. 2020 Jul;21:100426. doi: 10.1016/j.vprsr.2020.100426. Epub 2020 Jun 20.
Vector-borne pathogens are responsible for serious emerging diseases and Rangelia vitalii, the etiologic agent of canine rangeliosis, is one of the most pathogenic tick-borne pathogens for dogs in South America. This protozoan is transmitted by the Amblyomma aureolatum tick bite and the clinical features associated to the disease are fever, hemolytic anemia, jaundice, hepatosplenomegaly and bleeding from natural orifices, mainly from the ear egde. The reports of canine rangeliosis in Argentina are scarce. In the present study we report the detection of Rangelia vitalii in a naturally infected dog from Gualeguay, Entre Ríos, Argentina with history of tick infestation and clinical signs compatible with rangeliosis. An initial blood sample was positive to piroplasmids by blood smear examination and the molecular amplification of a fragment of the 18SrRNA gene. Sequencing of the fragment confirmed the pathogen identity. After treatment with imidocarb dipropionate, the clinical signs remitted and the blood smear tested negative.
虫媒病原体可导致严重的新发传染病，而兰格尔尼亚原虫是导致南美的犬传染性边虫病的最具致病性的蜱传病原体之一。这种原生动物通过安氏革蜱的叮咬传播，与疾病相关的临床特征包括发热、溶血性贫血、黄疸、肝脾肿大和自然孔出血，主要来自耳部边缘。阿根廷有关犬传染性边虫病的报道很少。在本研究中，我们报告了在阿根廷恩特雷里奥斯省瓜莱瓜伊的一只自然感染的狗中检测到兰格尔尼亚原虫，该狗有蜱虫感染史和与边虫病相符的临床症状。初始血液样本通过血涂片检查对梨形虫呈阳性，并且 18SrRNA 基因的片段的分子扩增呈阳性。片段的测序证实了病原体的身份。用二丙基咪唑苯并咪唑治疗后，临床症状缓解，血涂片检查呈阴性。
