血清β2-微球蛋白升高——持续性全身性淋巴结病患者发生艾滋病的预后标志物。
Elevated serum beta-2-microglobulin--a prognostic marker for development of AIDS among patients with persistent generalized lymphadenopathy.
作者信息
Morfeldt-Månson J, Julander I, von Stedingk L V, Wasserman J, Nilsson B
机构信息
Department of Infectious Diseases, Roslagstull Hospital, Karolinska Institute, Stockholm.
出版信息
Infection. 1988 Mar-Apr;16(2):109-10. doi: 10.1007/BF01644315.
For evaluation of its prognostic value, the level of serum beta-2-microglobulin was determined in early serum samples from 88 patients with persistent generalized lymphadenopathy in a prospective longitudinal study. Patients with serum beta-2-microglobulin greater than 2.6 mg/l were found to have a significantly higher risk of developing AIDS earlier when compared to patients with a lower level (p less than 0.001).
为评估其预后价值，在一项前瞻性纵向研究中，对88例持续性全身淋巴结肿大患者的早期血清样本测定了血清β2微球蛋白水平。发现血清β2微球蛋白大于2.6mg/L的患者与水平较低的患者相比，更早发展为艾滋病的风险显著更高（p<0.001）。
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