Cerebrospinal fluid neopterin and beta 2-microglobulin levels in neurologically asymptomatic HIV-infected patients before and after initiation of zidovudine treatment.
作者信息
Hagberg L, Norkrans G, Andersson M, Wachter H, Fuchs D
机构信息
Dept. of Infectious Diseases, University of Göteborg, Ostra Hospital, Sweden.
出版信息
Infection. 1992 Nov-Dec;20(6):313-5. doi: 10.1007/BF01710672.
PMID:1293049
Abstract
The effect of zidovudine on beta 2-microglobulin and neopterin in the cerebrospinal fluid (CSF) was studied in ten HIV-seropositive neurologically healthy individuals. CSF concentrations of neopterin decreased by 53% (from 20.3 to 9.5 nmol/l, p < 0.01) and beta 2-microglobulin by 36% (from 2.8 to 1.8 mg/l, p < 0.01) four to eight months after initiation of therapy.
摘要
Zotero 插件