Song Huiwen, Wang Xianbin, Lian Yubao, Wan Tuer
Department of Infectious Diseases, Saming First Hospital Affiliated with Fujian Medical University, Fujian Province, China.
Department of Imaging Medicine, Saming First Hospital Affiliated with Fujian Medical University, Fujian Province, China.
J Int Med Res. 2020 Aug;48(8):300060520949404. doi: 10.1177/0300060520949404.
Clinical characteristics of patients with pyogenic liver abscess (PLA) of varying etiologies may be different. This study aimed to analyze the clinical characteristics, pathogenic bacteria, treatment, and prognosis of patients with PLA associated with diabetes and biliary disease.
Clinical, imaging, and laboratory data from 202 inpatients with PLA were retrospectively analyzed.
Eighty-eight patients (43.6%) had a history of diabetes, 73 (36.1%) had a history of underlying biliary tract disease, and 24 (11.9%) had both the diseases. The level of C-reactive protein (CRP) increased in 99.2% (119/120) patients, and the level of procalcitonin (PCT) increased in 95.5% (148/155) patients. The main pathogen of PLA was . The incidence of bloodstream infection increased by 34.4% (22/64) in patients with PLA that was associated with diabetes mellitus, and that of infection was 88.6% (39/44). The readmission rate for patients with PLA with underlying biliary diseases was 10.2 to 12.5%.
The main pathogen of PLA is , which is sensitive to most antibiotics. Patients with PLA associated with diabetes were more likely to have bloodstream infections, and the recurrence rate of PLA with underlying biliary diseases was higher than without biliary duct disease.
不同病因的化脓性肝脓肿（PLA）患者的临床特征可能有所不同。本研究旨在分析合并糖尿病和胆道疾病的PLA患者的临床特征、病原菌、治疗及预后。
回顾性分析202例PLA住院患者的临床、影像和实验室数据。
88例患者（43.6%）有糖尿病史，73例（36.1%）有胆道疾病史，24例（11.9%）两种疾病都有。99.2%（119/120）的患者C反应蛋白（CRP）水平升高，95.5%（148/155）的患者降钙素原（PCT）水平升高。PLA的主要病原菌是 。合并糖尿病的PLA患者血流感染发生率增加34.4%（22/64）， 感染发生率为88.6%（39/44）。合并胆道疾病的PLA患者再入院率为10.2%至12.5%。
PLA的主要病原菌是 ，对大多数抗生素敏感。合并糖尿病的PLA患者更容易发生血流感染，合并胆道疾病的PLA患者复发率高于无胆道疾病者。
