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卡介苗免疫疗法诱发的恶性肿瘤所致霉菌性腹主动脉瘤

Mycotic abdominal aortic aneurysm induced by immunotherapy with bacille Calmette-Guérin vaccine for malignancy.

作者信息

Woods J M, Schellack J, Stewart M T, Murray D R, Schwartzman S W

机构信息

Department of Surgery, Emory University School of Medicine, Atlanta, GA.

出版信息

J Vasc Surg. 1988 Jun;7(6):808-10. doi: 10.1067/mva.1988.avs0070808.

Abstract

Successful surgical treatment of a mycotic abdominal aortic aneurysm infected with Mycobacterium bovis is described. The infecting organism can be traced to an intraneoplastic injection of bacille Calmette-Guérin (BCG) vaccine into a cutaneous malignant melanoma nodule 14 months before aneurysm detection (17 months before operation). Treatment consisted of aneurysm excision, in situ prosthetic graft placement, and antituberculous medications. This patient represents the first reported case of BCG-induced mycotic aortic aneurysm.

摘要

本文描述了一例成功手术治疗牛分枝杆菌感染的霉菌性腹主动脉瘤的病例。感染源可追溯至在动脉瘤发现前14个月(手术前17个月),曾将卡介苗(BCG)瘤内注射到皮肤恶性黑色素瘤结节中。治疗包括动脉瘤切除、原位植入人工血管移植物以及抗结核药物治疗。该患者是首例报道的卡介苗诱发的霉菌性主动脉瘤病例。

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