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越南两例人体肺和心脏感染俄氏棘球绦虫病例

Two Human Cases of Echinococcus ortleppi Infection in the Lung and Heart in Vietnam.

作者信息

De Nguyen Van, Minh Pham Ngoc, Duyet Le Van, Bich Nguyen Ngoc, Son Trinh Nam, Jung Bong-Kwang, Chai Jong-Yil

机构信息

Department of Parasitology, Hanoi Medical University, Hanoi, Vietnam.

National Hospital of Tropical Diseases, Hanoi, Vietnam.

出版信息

Korean J Parasitol. 2020 Aug;58(4):451-456. doi: 10.3347/kjp.2020.58.4.451. Epub 2020 Aug 25.

Abstract

This is a report of 2 cases of human hydatidosis caused by Echinococcus ortleppi in Vietnam. The patients were a 12-year-old male (case 1) having a cyst of 10.0×9.0 cm size in the lung and a 50-year-old female with a 3.0×3.3 cm-sized cyst in the heart. Eosinophilia was 33.7% in the male and 45.8% in the female patient. C-reactive protein was increased to 16.5 mg/L in the male and 18.2 mg/L in the female. Both patients were positive for ELISA at OD=2.5 and 3.1, respectively. Echinococcus protoscolices were collected from the cysts by amniocentesis and surgery. The protoscolices were identified as E. ortleppi by morphology and analysis of mitochondrial NADH dehydrogenase 1 (nad1) gene sequence. Both patients were cured by surgical resection of the hydatid cyst combined with albendazole medication. The E. ortleppi infection in lung is the second report, and the other in the heart is the first in Vietnam.

摘要

这是一篇关于越南由奥氏棘球绦虫引起的2例人体包虫病的报告。患者为一名12岁男性(病例1),肺部有一个大小为10.0×9.0厘米的囊肿,以及一名50岁女性,心脏有一个大小为3.0×3.3厘米的囊肿。男性患者嗜酸性粒细胞增多症为33.7%,女性患者为45.8%。男性患者C反应蛋白升高至16.5毫克/升,女性患者为18.2毫克/升。两名患者ELISA检测分别在OD = 2.5和3.1时呈阳性。通过羊膜穿刺术和手术从囊肿中收集到原头节。通过形态学和线粒体烟酰胺腺嘌呤二核苷酸脱氢酶1(nad1)基因序列分析,将原头节鉴定为奥氏棘球绦虫。两名患者均通过手术切除包虫囊肿并联合使用阿苯达唑药物治愈。肺部的奥氏棘球绦虫感染是越南的第二例报告,心脏的感染则是首例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/01a3/7462803/94ddc31c40ca/kjp-58-4-451f1.jpg

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