在波兰首例人类包虫病病例报告。
First Report of in Human Cases of Cystic Echinococcosis in Poland.
机构信息
Chair and Department of General Biology and Parasitology, Medical University of Warsaw, 5 Chałubińskiego Street, 02-004 Warsaw, Poland.
Department of Infectious Diseases, Tropical, and Hepatology, Medical University of Warsaw, 37 Wolska Street, 01-201 Warsaw, Poland.
出版信息
Biomed Res Int. 2019 Apr 8;2019:2474839. doi: 10.1155/2019/2474839. eCollection 2019.
Cystic echinococcosis is considered as an emerging zoonosis that can develop asymptomatically for years, clinically nonpathognomic. The disease is of public health importance due to often late, difficult diagnostics, uncertain results of treatment, the need to remove hydatid cysts surgically in advanced cases, and poor prognosis in untreated patients. Six Polish female patients with diagnosed cystic echinococcosis (CE) were examined. DNA extracted from the liver and lung samples served for amplification of mitochondrial gene fragment. Sequence alignments of 5 isolates showed identity with the pig strain, G7. One case was in 100% identical with G5, the cattle strain. These data demonstrate first report of , regarded as extinct species, causing human cystic echinococcosis in Poland, where the most frequent causative agent of human CE is .
囊性包虫病被认为是一种新出现的人畜共患病，可多年无症状地发展，临床上无特征性表现。由于常常出现晚期、难以诊断、治疗效果不确定、在晚期病例中需要手术切除包虫囊肿以及未经治疗的患者预后不良，该病对公共卫生具有重要意义。我们检查了 6 名被诊断为囊性包虫病（CE）的波兰女性患者。从肝和肺样本中提取的 DNA 用于扩增线粒体基因片段。对 5 个分离株的序列比对显示与猪株 G7 具有同一性。1 例与牛株 G5 完全相同。这些数据首次表明，被认为已经灭绝的物种在波兰导致了人类囊性包虫病，而在波兰，导致人类 CE 的最常见病原体是 。
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