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由韩国典型培养物保藏中心(KCCM)80188号保藏菌株生产的一水合L-谷氨酸钠作为所有动物物种饲料添加剂的安全性和有效性。

Safety and efficacy of monosodium l-glutamate monohydrate produced by KCCM 80188 as a feed additive for all animal species.

作者信息

Bampidis Vasileios, Azimonti Giovanna, Bastos Maria de Lourdes, Christensen Henrik, Dusemund Birgit, Kos Durjava Mojca, Kouba Maryline, López-Alonso Marta, López Puente Secundino, Marcon Francesca, Mayo Baltasar, Pechová Alena, Petkova Mariana, Ramos Fernando, Sanz Yolanda, Villa Roberto Edoardo, Woutersen Ruud, Herman Lieve, Glandorf Boet, Saarela Maria, Galobart Jaume, Holczknecht Orsolya, Manini Paola, Pettenati Elisa, Tarrés Call Jordi, Pizzo Fabiola, Anguita Montserrat

出版信息

EFSA J. 2020 Apr 28;18(4):e06085. doi: 10.2903/j.efsa.2020.6085. eCollection 2020 Apr.

DOI:10.2903/j.efsa.2020.6085
PMID:32874293
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7448065/
Abstract

Following a request from the European Commission, the Panel on Additives and Products or substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on the safety and efficacy of monosodium l-glutamate monohydrate produced by fermentation using KCCM 80188 when used as a sensory additive (flavouring compound) in feed and water for drinking for all animal species. The production strain is not genetically modified. Viable cells of the production strain were not detected in the final additive. The additive does not give rise to any safety concern regarding the production strain. Monosodium l-glutamate monohydrate produced using KCCM 80188 is considered safe for the target species, for the consumer and for the environment. Monosodium l-glutamate monohydrated produced by KCCM 80188 is considered not toxic by inhalation, not irritant to skin or eyes and not a dermal sensitiser. The FEEDAP Panel expressed reservations on the use of the additive in water for drinking due to concerns on its impact on the hygienic conditions of the water. The Panel concluded that the additive is efficacious to contribute to the flavour of feed.

摘要

应欧盟委员会要求,动物饲料添加剂及产品或物质专家小组(FEEDAP)被要求就发酵法生产的L-谷氨酸钠一水合物(使用KCCM 80188)作为感官添加剂(调味化合物)用于所有动物物种的饲料和饮用水时的安全性和有效性提供科学意见。生产菌株未经过基因改造。在最终添加剂中未检测到生产菌株的活细胞。该添加剂对生产菌株不存在任何安全问题。使用KCCM 80188生产的L-谷氨酸钠一水合物对目标物种、消费者和环境而言被认为是安全的。使用KCCM 80188生产的L-谷氨酸钠一水合物被认为吸入无毒、对皮肤或眼睛无刺激性且不是皮肤致敏剂。由于担心其对水卫生状况的影响,FEEDAP专家小组对该添加剂用于饮用水表示保留意见。专家小组得出结论,该添加剂有助于改善饲料风味,是有效的。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb44/7448065/5eef69e2beb6/EFS2-18-e06085-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb44/7448065/5eef69e2beb6/EFS2-18-e06085-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb44/7448065/5eef69e2beb6/EFS2-18-e06085-g001.jpg

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本文引用的文献

1
Scientific Opinion on the update of the list of QPS-recommended biological agents intentionally added to food or feed as notified to EFSA (2017-2019).关于向欧洲食品安全局通报的(2017 - 2019年)有意添加到食品或饲料中的QPS推荐生物制剂清单更新的科学意见。
EFSA J. 2020 Feb 3;18(2):e05966. doi: 10.2903/j.efsa.2020.5966. eCollection 2020 Feb.
2
Guidance on the assessment of the safety of feed additives for the environment.饲料添加剂对环境安全性的评估指南。
EFSA J. 2019 Apr 5;17(4):e05648. doi: 10.2903/j.efsa.2019.5648. eCollection 2019 Apr.
3
Guidance on the assessment of the efficacy of feed additives.
饲料添加剂功效评估指南。
EFSA J. 2018 May 7;16(5):e05274. doi: 10.2903/j.efsa.2018.5274. eCollection 2018 May.
4
Guidance on the characterisation of microorganisms used as feed additives or as production organisms.用作饲料添加剂或生产生物的微生物特性鉴定指南。
EFSA J. 2018 Mar 28;16(3):e05206. doi: 10.2903/j.efsa.2018.5206. eCollection 2018 Mar.
5
Re-evaluation of glutamic acid (E 620), sodium glutamate (E 621), potassium glutamate (E 622), calcium glutamate (E 623), ammonium glutamate (E 624) and magnesium glutamate (E 625) as food additives.对谷氨酸(E 620)、谷氨酸钠(E 621)、谷氨酸钾(E 622)、谷氨酸钙(E 623)、谷氨酸铵(E 624)和谷氨酸镁(E 625)作为食品添加剂的重新评估。
EFSA J. 2017 Jul 12;15(7):e04910. doi: 10.2903/j.efsa.2017.4910. eCollection 2017 Jul.
6
Guidance on the identity, characterisation and conditions of use of feed additives.饲料添加剂的标识、特性及使用条件指南。
EFSA J. 2017 Oct 17;15(10):e05023. doi: 10.2903/j.efsa.2017.5023. eCollection 2017 Oct.
7
Guidance on the assessment of the safety of feed additives for the target species.目标物种饲料添加剂安全性评估指南。
EFSA J. 2017 Oct 17;15(10):e05021. doi: 10.2903/j.efsa.2017.5021. eCollection 2017 Oct.
8
Evaluation of certain food additives and contaminants. Thirty-first report of the Joint FAO/WHO Expert Committee on Food Additives.某些食品添加剂及污染物的评估。联合国粮农组织/世界卫生组织食品添加剂联合专家委员会第三十一次报告。
World Health Organ Tech Rep Ser. 1987;759:1-53.