Bampidis Vasileios, Azimonti Giovanna, Bastos Maria de Lourdes, Christensen Henrik, Dusemund Birgit, Kouba Maryline, Kos Durjava Mojca, López-Alonso Marta, López Puente Secundino, Marcon Francesca, Mayo Baltasar, Pechová Alena, Petkova Mariana, Ramos Fernando, Sanz Yolanda, Villa Roberto Edoardo, Woutersen Ruud, Cocconcelli Pier Sandro, Glandorf Boet, Herman Lieve, Prieto Maradona Miguel, Saarela Maria, Tosti Luca, Anguita Montserrat, Galobart Jaume, Holczknecht Orsolya, Manini Paola, Pizzo Fabiola, Tarrés-Call Jordi, Pettenati Elisa
EFSA J. 2020 May 27;18(5):e06140. doi: 10.2903/j.efsa.2020.6140. eCollection 2020 May.
Following a request from the European Commission, the Panel on Additives and Products or substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on the safety and efficacy of disodium 5'-inosinate (IMP) produced by fermentation using KCCM 80161 when used as a sensory additive (flavouring compound) in feed and water for drinking for all animal species. The production strain is not genetically modified. Viable cells of the production strain were not detected in the final additive. The additive does not give rise to any safety concern regarding the production strain. IMP produced using KCCM 80161 is considered safe for the target species, for the consumer and for the environment. IMP produced using KCCM 80161 is considered not toxic by inhalation, not irritant to skin or eyes and not a dermal sensitiser. The FEEDAP Panel expressed reservations on the use of the additive in water for drinking due to concerns on its impact on the hygienic conditions of the water. The Panel concluded that the additive is efficacious to contribute to the flavour of feed.
应欧盟委员会的要求，动物饲料添加剂及产品或物质专家委员会（FEEDAP）被要求就使用KCCM 80161发酵生产的5'-肌苷酸二钠（IMP）作为所有动物物种饲料和饮用水中的感官添加剂（调味化合物）的安全性和有效性发表科学意见。生产菌株未经过基因改造。在最终添加剂中未检测到生产菌株的活细胞。该添加剂对生产菌株不存在任何安全问题。使用KCCM 80161生产的IMP被认为对目标物种、消费者和环境是安全的。使用KCCM 80161生产的IMP被认为吸入无毒、对皮肤或眼睛无刺激性且不是皮肤致敏剂。由于担心其对水卫生条件的影响，FEEDAP专家委员会对该添加剂在饮用水中的使用表示保留意见。专家委员会得出结论，该添加剂有助于饲料调味，是有效的。
