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坦桑尼亚创伤性脊柱损伤的手术治疗:手术管理、神经学结果及手术时机

Operative Treatment of Traumatic Spinal Injuries in Tanzania: Surgical Management, Neurologic Outcomes, and Time to Surgery.

作者信息

Magogo Juma, Lazaro Albert, Mango Mechris, Zuckerman Scott L, Leidinger Andreas, Msuya Salim, Rutabasibwa Nicephorus, Shabani Hamisi K, Härtl Roger

机构信息

Muhimbili Orthopedic Institute, Dar es Salaam, Tanzania.

New York-Presbyterian Hospital, Weill Cornell Medical College, New York, NY, USA.

出版信息

Global Spine J. 2021 Jan;11(1):89-98. doi: 10.1177/2192568219894956. Epub 2020 Jan 21.

Abstract

STUDY DESIGN

Retrospective case series.

OBJECTIVE

Little is known about operative management of traumatic spinal injuries (TSI) in low- and middle-income countries (LMIC). In patients undergoing surgery for TSI in Tanzania, we sought to (1) determine factors involved in the operative decision-making process, specifically implant availability and surgical judgment; (2) report neurologic outcomes; and (3) evaluate time to surgery.

METHODS

All patients from October 2016 to June 2019 who presented with TSI and underwent surgical stabilization. Fracture type, operation, neurologic status, and time-to-care was collected.

RESULTS

Ninety-seven patients underwent operative stabilization, 23 (24%) cervical and 74 (77%) thoracic/lumbar. Cervical operations included 4 (17%) anterior cervical discectomy and fusion with plate, 7 (30%) anterior cervical corpectomy with tricortical iliac crest graft and plate, and 12 (52%) posterior cervical laminectomy and fusion with lateral mass screws. All 74 (100%) of thoracic/lumbar fractures were treated with posterolateral pedicle screws. Short-segment fixation was used in 86%, and constructs often ended at an injured (61%) or junctional (62%) level. Sixteen (17%) patients improved at least 1 ASIA grade. The sole predictor of neurologic improvement was faster time from admission to surgery (odds ratio = 1.04, = .011, 95%CI = 1.01-1.07). Median (range) time in days included: injury to admission 2 (0-29), admission to operating room 23 (0-81), and operating room to discharge 8 (2-31).

CONCLUSIONS

In a cohort of LMIC patients with TSI undergoing stabilization, the principle driver of operative decision making was cost of implants. Faster time from admission to surgery was associated with neurologic improvement, yet significant delays to surgery were seen due to patients' inability to pay for implants. Several themes for improvement emerged: early surgery, implant availability, prehospital transfer, and long-term follow-up.

摘要

研究设计

回顾性病例系列研究。

目的

在低收入和中等收入国家(LMIC),对于创伤性脊柱损伤(TSI)的手术治疗了解甚少。在坦桑尼亚接受TSI手术的患者中,我们试图:(1)确定手术决策过程中涉及的因素,特别是植入物的可获得性和手术判断;(2)报告神经学结果;(3)评估手术时间。

方法

收集2016年10月至2019年6月期间所有出现TSI并接受手术固定的患者的骨折类型、手术方式、神经学状态和就医时间。

结果

97例患者接受了手术固定,其中23例(24%)为颈椎损伤,74例(77%)为胸腰椎损伤。颈椎手术包括4例(17%)前路颈椎间盘切除融合术并使用钢板,7例(30%)前路颈椎椎体次全切除并使用三面皮质髂骨移植和钢板,12例(52%)后路颈椎椎板切除融合术并使用侧块螺钉。所有74例(100%)胸腰椎骨折均采用后外侧椎弓根螺钉治疗。86%采用短节段固定,固定结构通常止于损伤节段(61%)或交界节段(62%)。16例(17%)患者的美国脊髓损伤协会(ASIA)分级至少提高了1级。神经功能改善的唯一预测因素是从入院到手术的时间更快(比值比=1.04,P =.011,95%置信区间=1.01 - 1.07)。以天为单位的中位(范围)时间包括:受伤至入院2(0 - 29)天,入院至手术室23(0 - 81)天,手术室至出院8(2 - 31)天。

结论

在一组接受固定治疗的LMIC TSI患者中,手术决策的主要驱动因素是植入物的成本。从入院到手术的时间更快与神经功能改善相关,但由于患者无力支付植入物费用,手术出现了显著延迟。出现了几个需要改进的主题:早期手术、植入物的可获得性、院前转运和长期随访。

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