酵母的变应原交叉反应性。

Allergenic cross-reactivity of yeasts.

作者信息

Koivikko A, Kalimo K, Nieminen E, Savolainen J, Viljanen M, Viander M

机构信息

Department of Pediatrics, University of Turku, Finland.

出版信息

Allergy. 1988 Apr;43(3):192-200. doi: 10.1111/j.1398-9995.1988.tb00418.x.

DOI:10.1111/j.1398-9995.1988.tb00418.x

PMID:3287997

Abstract

Yeast allergen extracts of Candida albicans, C. pseudotropicalis, C. krusei, C. parapsilosis, C. tropicalis, C. guilliermondi, C. humicola, C. norwegica, C. utilis, Cryptococcus albidus, Geotrichum candidum, Pityrosporon pachydermatis, P. ovale, Rhodotorula minuta, R. rubra, Saccharomyces cerevisiae, Torulopsis glabrata and Trichosporon cutaneum were investigated regarding their common allergenic properties. The enzyme immunoassay (EIA) using rabbit anti-Candida albicans antiserum showed remarkable immunological cross-reactivity only between the Candida species. However, there was a significant multiple sensitivity to the extracts of C. albicans, C. utilis, Cr. albidus, R. rubra and S. cerevisiae in skin prick testing in atopic patients, suggesting the possible presence of one or more common skin reactive allergens.

摘要

研究了白色念珠菌、伪热带念珠菌、克鲁斯念珠菌、近平滑念珠菌、热带念珠菌、季也蒙念珠菌、土生念珠菌、挪威念珠菌、产朊假丝酵母、白隐球菌、白地霉、厚皮马拉色菌、卵形马拉色菌、微小隐球酵母、深红酵母、酿酒酵母、光滑球拟酵母和皮状丝孢酵母的酵母过敏原提取物的共同致敏特性。使用兔抗白色念珠菌抗血清的酶免疫测定（EIA）仅在念珠菌属之间显示出显著的免疫交叉反应性。然而，在特应性患者的皮肤点刺试验中，对白色念珠菌、产朊假丝酵母、白隐球菌、深红酵母和酿酒酵母的提取物存在显著的多重敏感性，这表明可能存在一种或多种常见的皮肤反应性过敏原。