幽门注射肉毒杆菌毒素治疗胃轻瘫导致的全身性肉毒中毒毒性
Systemic Botulism Toxicity Caused by Pyloric Botox Injection to Treat Gastroparesis.
作者信息
Bensen Gordon P, Rutherford Cristina C, Gardner Timothy B
机构信息
Section of Gastroenterology and Hepatology, Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire, USA.
出版信息
Case Rep Gastroenterol. 2020 Jul 28;14(2):373-376. doi: 10.1159/000508854. eCollection 2020 May-Aug.
Abstract
Systemic botulism resulting from therapeutic Botox (OnabotulinumtoxinA) injection has been rarely reported, and never in the context of pylorus injection to treat gastroparesis. We report the case of a 27-year-old female with Emery-Dreifuss muscular dystrophy who developed severe systemic botulism toxicity following the intrapyloric injection of 100 units of Botox to treat gastroparesis. The patient eventually made a full recovery.
摘要
由治疗性肉毒杆菌毒素（A型肉毒毒素）注射导致的全身性肉毒中毒鲜有报道，在幽门注射治疗胃轻瘫的情况下更是从未有过。我们报告了一例27岁患有埃默里 - 德赖富斯肌营养不良症的女性病例，该患者在幽门内注射100单位肉毒杆菌毒素以治疗胃轻瘫后，出现了严重的全身性肉毒中毒毒性反应。患者最终完全康复。
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