Tabuenca Del Barrio Laura, Mozo Cuadrado Marcos, Nova Camacho Luiz Miguel, Zubicoa Enériz Alicia, Aranguren Laflin Miren Dolores, Alcaine Soler Araceli
Ophthalmology, Complejo Hospitalario de Navarra, Pamplona, Navarra, Spain.
Pathology, Complejo Hospitalario de Navarra, Pamplona, Navarra, Spain.
GMS Ophthalmol Cases. 2020 Aug 6;10:Doc30. doi: 10.3205/oc000157. eCollection 2020.
To emphasize the importance of an early diagnosis and an adequate treatment in conjunctival tumors. We present two clinical cases and compare the course of each case: one of conjunctival intraepithelial neoplasia (CIN) which took a positive course, and a fatal case of squamous cell carcinoma (SCC) with intraocular and orbital extension. Epithelial conjunctival malignancies are one of the most prevalent ocular surface tumors. Among these, CIN are the most common. CIN have an excellent prognosis, given adequate treatment. However, when the diagnosis of CIN is late, the epithelial basement membrane will be affected, resulting in SCC. SCC may have poorer results due to its capacity to infiltrate near tissues and create distant metastasis. It is not common today to treat patients with orbital extension of SCC; however, it is crucial to note the importance of an early diagnosis of conjunctival malignancies. An early diagnosis is essential to prevent the transformation to other life-threatening types.
为强调结膜肿瘤早期诊断和充分治疗的重要性，我们呈现两例临床病例并比较每个病例的病程：一例结膜上皮内瘤变（CIN）呈良性病程，另一例鳞状细胞癌（SCC）伴眼内及眶内侵犯的致命病例。结膜上皮恶性肿瘤是最常见的眼表肿瘤之一。其中，CIN最为常见。给予充分治疗的情况下，CIN预后良好。然而，当CIN诊断较晚时，上皮基底膜会受到影响，从而导致SCC。SCC由于其浸润周围组织及发生远处转移的能力，可能预后较差。如今，治疗伴有眶内侵犯的SCC患者并不常见；然而，必须注意结膜恶性肿瘤早期诊断的重要性。早期诊断对于预防其转变为其他危及生命的类型至关重要。
