Department of Physical Education and Sport, University of Granada, 18071 Granada, Spain.
Int J Environ Res Public Health. 2020 Sep 2;17(17):6397. doi: 10.3390/ijerph17176397.
This study investigated the effects of a 24-week combined training program (CTP) based on strength exercises and cognitive-motor tasks performed concurrently in participants with multiple sclerosis. A randomized, controlled intervention study was carried out. In total, 31 subjects with a confirmed diagnosis of multiple sclerosis (14 men and 17 women) were stratified and randomized into an intervention group (17 subjects) and a control group (14 subjects). The intervention group completed three weekly training sessions for 24 weeks, while the control group pursued their normal daily activities. In this program, cognitive-motor tasks were completed at once (dual tasking). A 3D photogrammetry connected to a selective attention system designed for dual tasking while walking was used. Ground reaction forces were measured using two force plates, one for sit-to-stand testing, while the other was used for static force measurement. Postural equilibrium was examined using a stabilometric plate based for Romberg test assessment. The 24-week training program for multiple sclerosis patients improved their static peak force by 11% ( < 0 .05), their rate of force development by 36% ( < 0.05), and their balance ( < 0.05). Performance in daily activities such as walking or sitting-to-standing improved significantly in multiple sclerosis participants. CTP training was effective in reducing the dual-task costs of step length (48%) and walking velocity (54%), as compared to a matched control group.
本研究调查了一项为期 24 周的综合训练计划（CTP）对多发性硬化症患者的影响。该计划结合了力量练习和认知运动任务。采用了一项随机对照干预研究。共有 31 名经确诊患有多发性硬化症的患者（14 名男性，17 名女性）参与，他们被分层并随机分为干预组（17 名患者）和对照组（14 名患者）。干预组每周完成三次训练，共 24 周，而对照组则进行正常的日常活动。在该计划中，认知运动任务同时完成（双重任务）。使用了一种连接到专为双重任务行走设计的选择性注意系统的 3D 摄影测量技术。使用两个测力板测量地面反作用力，一个用于坐站测试，另一个用于静态力测量。使用基于 Romberg 测试评估的稳定平台来检查姿势平衡。24 周的多发性硬化症患者训练计划使他们的静态峰值力量提高了 11%（ < 0.05），力量发展速度提高了 36%（ < 0.05），平衡能力提高了（ < 0.05）。多发性硬化症参与者的日常活动（如行走或坐站）的表现显著改善。与匹配的对照组相比，CTP 训练可有效降低步长（48%）和步行速度（54%）的双重任务成本。
